1-Triazene,1-(4-chlorophenyl)-3,3-dimethyl-
名称
[ CAS 号 ]:
7203-90-9
[ 英文名 ]:
1-Triazene,1-(4-chlorophenyl)-3,3-dimethyl-
[英文别名 ]:
- 1-p-Chlorfenyl-3,3-dimethyltriazen
物理化学性质
[ 密度 ]:
1.14g/cm3
[ 沸点 ]:
243.8ºC at 760 mmHg
[ 分子式 ]:
C8H10ClN3
[ 分子量 ]:
183.63800
[ 闪点 ]:
101.2ºC
[ 精确质量 ]:
183.05600
[ PSA ]:
27.96000
[ LogP ]:
2.90030
[ 折射率 ]:
1.55
毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- XY0700000
- CHEMICAL NAME :
- Triazene, 3,3-dimethyl-1-(p-chlorophenyl)-
- CAS REGISTRY NUMBER :
- 7203-90-9
- LAST UPDATED :
- 199709
- DATA ITEMS CITED :
- 12
- MOLECULAR FORMULA :
- C8-H10-Cl-N3
- MOLECULAR WEIGHT :
- 183.66
- WISWESSER LINE NOTATION :
- GR DNUNN1&1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 362 mg/kg
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - structural or functional change in trachea or bronchi Liver - other changes Blood - changes in cell count (unspecified)
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 330 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 3200 mg/kg/70W-I
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Kidney, Ureter, Bladder - Kidney tumors Musculoskeletal - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 300 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria Brain and Coverings - tumors Kidney, Ureter, Bladder - Kidney tumors
- TYPE OF TEST :
- Sex chromosome loss and nondisjunction
- TYPE OF TEST :
- Micronucleus test
MUTATION DATA
- TYPE OF TEST :
- Host-mediated assay
- TEST SYSTEM :
- Rodent - mouse Yeast - Saccharomyces cerevisiae
- DOSE/DURATION :
- 73464 mg/kg
- REFERENCE :
- CBINA8 Chemico-Biological Interactions. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1969- Volume(issue)/page/year: 9,365,1974
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