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胞内蛋白酶赖氨酸-C

胞内蛋白酶赖氨酸-C用途

内蛋白酶Lys-C是一种在赖氨酸残基C端切割蛋白质的蛋白酶,通常用于蛋白质测序[1]。

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胞内蛋白酶赖氨酸-C名称

[ CAS 号 ]:
72561-05-8

[ 中文名 ]:
胞内蛋白酶赖氨酸-C

[ 英文名 ]:
Endoproteinase Lys-C

[英文别名 ]:

Endoproteinase Lys-C, ExcisionGrade
Endoproteinase Lys-C from Lysobacter enzymogenes
MFCD02253020
protease from lysobacter enzymogenes
EINECS 276-716-4

胞内蛋白酶赖氨酸-C生物活性

[ 描述 ]:

内蛋白酶Lys-C是一种在赖氨酸残基C端切割蛋白质的蛋白酶,通常用于蛋白质测序[1]。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[参考文献]

[1]. P A Jekel, et al. Use of endoproteinase Lys-C from Lysobacter enzymogenes in protein sequence analysis. Anal Biochem. 1983 Oct 15;134(2):347-54.

胞内蛋白酶赖氨酸-C物理化学性质

[ 密度 ]:
1.3±0.1 g/cm3

[ 沸点 ]:
781.9±60.0 °C at 760 mmHg

[ 分子式 ]:
C₃₀H₂₇N₃O₅

[ 分子量 ]:
509.552

[ 闪点 ]:
426.7±32.9 °C

[ 精确质量 ]:
509.195068

[ LogP ]:
3.97

[ 外观性状 ]:
lyophilized powder

[ 蒸汽压 ]:
0.0±2.8 mmHg at 25°C

[ 折射率 ]:
1.663

[ 储存条件 ]:
2-8°C

胞内蛋白酶赖氨酸-C安全信息

[ 符号 ]:

GHS07, GHS08

[ 信号词 ]:
Danger

[ 危害声明 ]:
H315-H317-H319-H334-H335

[ 警示性声明 ]:
P261-P280-P305 + P351 + P338-P342 + P311

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ 危害码 (欧洲) ]:
Xn

[ 风险声明 (欧洲) ]:
R36/37/38;R42/43

[ 安全声明 (欧洲) ]:
S22;S26;S45;S36/S37

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

胞内蛋白酶赖氨酸-C文献

Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

Anal. Chem. 81(11) , 4493-501, (2009)

The analysis of proteome-wide phosphorylation events is still a major analytical challenge because of the enormous complexity of protein phosphorylation networks. In this work, we evaluate the complem...

Identification of the lysine residue responsible for coenzyme A binding in the heterodimeric 2-oxoacid:ferredoxin oxidoreductase from Sulfolobus tokodaii, a thermoacidophilic archaeon, using 4-fluoro-7-nitrobenzofurazan as an affinity label

Biochim. Biophys. Acta 1794(2) , 335-40, (2009)

The heterodimeric 2-oxoacid:ferredoxin oxidoreductase (StOFOR) from Sulfolobus tokodaii, a thermoacidophilic archaeon, was inactivated by low concentrations of 4-fluoro-7-nitrobenzofurazan (NBD-F), wi...

Proteomic analysis of annexin A2 phosphorylation induced by microtubule interfering agents and kinesin spindle protein inhibitors.

J. Proteome Res. 9 , 4649-4660, (2010)

Microtubule interfering agents (MIAs) are antitumor drugs that inhibit microtubule dynamics, while kinesin spindle protein (KSP) inhibitors are substances that block the formation of the bipolar spind...

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