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溴甲纳曲酮

溴甲纳曲酮用途

Methylnaltrexone Bromide 是一种有效的阿片受体 (opioid receptor) 拮抗剂，能够降低肠道内由阿片类物质导致的便秘症状。

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溴甲纳曲酮名称

[ CAS 号 ]:
73232-52-7

[ 中文名 ]:
溴甲纳曲酮

[ 英文名 ]:
Methylnaltrexone (Bromide)

[英文别名 ]:

[14C]-N-Methylnaltrexone bromide
MNTX bromide
Naltrexone methobromide
(-)-naltrexone methyl bromide
Relistor
Methylnaltrexone (Bromide)
MRZ-2663BR
MOA-728
Relistor (TN)
MNTX

溴甲纳曲酮物理化学性质

[ 熔点 ]:
237-239ºC

[ 分子式 ]:
C₂₁H₂₆BrNO₄

[ 分子量 ]:
436.33900

[ 精确质量 ]:
435.10500

[ PSA ]:
69.59000

[ LogP ]:
3.02510

[ 储存条件 ]:
-20°C，惰性气体

溴甲纳曲酮MSDS

溴甲纳曲酮安全信息

[ 符号 ]:

GHS06, GHS09

[ 信号词 ]:
Danger

[ 危害声明 ]:
H301-H400

[ 警示性声明 ]:
P273-P301 + P310

[ 危险品运输编码 ]:
UN 2811 6.1 / PGIII

[ RTECS号 ]:
QD0188550

溴甲纳曲酮合成路线

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溴甲纳曲酮文献

Efficacy of pharmacological therapies for the treatment of opioid-induced constipation: systematic review and meta-analysis.

Am. J. Gastroenterol. 108(10) , 1566-74; quiz 1575, (2013)

There has been no definitive synthesis of the evidence for any benefit of available pharmacological therapies in opioid-induced constipation (OIC). We conducted a systematic review and meta-analysis t...

[Opiate induced constipation--mechanisms, relevance and treatment].

Dtsch. Med. Wochenschr. 138(43) , 2207-11, (2013)

Effects of remifentanil on the esophagogastric junction and swallowing.

Acta Anaesthesiol. Scand. 57(8) , 1002-9, (2013)

A recent study demonstrated that reflux is associated with impaired pressure augmentation in the esophagogastric junction (EGJ), caused by diaphragmal contractions during inspiration. It is unknown wh...

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溴甲纳曲酮

溴甲纳曲酮用途

溴甲纳曲酮名称

溴甲纳曲酮物理化学性质

溴甲纳曲酮MSDS

详细MSDS(安全技术说明书)

溴甲纳曲酮安全信息

溴甲纳曲酮合成路线

详细合成路线

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