DL-3-BENZOYLOXYQUINUCLIDINE HYDROCHLORIDE
名称
[ CAS 号 ]:
7348-26-7
[ 英文名 ]:
DL-3-BENZOYLOXYQUINUCLIDINE HYDROCHLORIDE
[英文别名 ]:
- Oxylidinum
- Oxylidine
- Quinuclidinol,benzoate,hydrochloride
- 3-Benzoyloxyquinuclidine hydrochloride
物理化学性质
[ 密度 ]:
1.18g/cm3
[ 沸点 ]:
333.7ºC at 760 mmHg
[ 分子式 ]:
C14H18ClNO2
[ 分子量 ]:
267.75100
[ 闪点 ]:
125.4ºC
[ 精确质量 ]:
267.10300
[ PSA ]:
29.54000
[ LogP ]:
3.02510
毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- VD6250000
- CHEMICAL NAME :
- Quinuclidinol, benzoate, hydrochloride
- CAS REGISTRY NUMBER :
- 7348-26-7
- LAST UPDATED :
- 198910
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C14-H17-N-O2.Cl-H
- MOLECULAR WEIGHT :
- 267.78
- WISWESSER LINE NOTATION :
- T66 A B CNTJ AOVR &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 250 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FAZMAE Fortschritte der Arzneimittelforschung. Progress in Drug Research. (Birkhauser Boston, Inc., c/o Springer-Verlag New York, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1959- Volume(issue)/page/year: 13,293,1969
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 250 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FAZMAE Fortschritte der Arzneimittelforschung. Progress in Drug Research. (Birkhauser Boston, Inc., c/o Springer-Verlag New York, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1959- Volume(issue)/page/year: 13,293,1969
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 225 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FAZMAE Fortschritte der Arzneimittelforschung. Progress in Drug Research. (Birkhauser Boston, Inc., c/o Springer-Verlag New York, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1959- Volume(issue)/page/year: 13,293,1969
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 35 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FAZMAE Fortschritte der Arzneimittelforschung. Progress in Drug Research. (Birkhauser Boston, Inc., c/o Springer-Verlag New York, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1959- Volume(issue)/page/year: 13,293,1969
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Parenteral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 280 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 33,70,1970
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