雷尼替丁-N-氧化物

雷尼替丁-N-氧化物用途

Ranitidine-N-oxide is a metabolite of Ranitidine. Ranitidine is a histamine H2-receptor antagonist, inhibiting the normal and meal-stimulated secretion of stomach acid. Ranitidine, sold under the trade name Zantac among others, is a medication which decreases stomach acid production.

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雷尼替丁-N-氧化物名称

[ CAS 号 ]:
73857-20-2

[ 中文名 ]:
雷尼替丁-N-氧化物

[ 英文名 ]:
Ranitidine-N-Oxide

[英文别名 ]:

Ranitidine-N-Oxide
Ranitidine Impurity 5

雷尼替丁-N-氧化物物理化学性质

[ 分子式 ]:
C₁₃H₂₂N₄O₄S

[ 分子量 ]:
330.40300

[ 精确质量 ]:
330.13600

[ PSA ]:
137.75000

[ LogP ]:
2.79750

雷尼替丁-N-氧化物毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KM6559250

CHEMICAL NAME :: 1,1-Ethenediamine, N-(2-(((5-((dimethylamino)methyl)-2-furanyl)methyl)th io)ethyl)-N'-methyl- 2-nitro-, N-oxide

CAS REGISTRY NUMBER :: 73857-20-2

LAST UPDATED :: 199209

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C13-H22-N4-O4-S

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >1 gm/kg

TOXIC EFFECTS :: Liver - other changes

REFERENCE :: JTSCDR Journal of Toxicological Sciences. (Japanese Soc. of Toxicological Sciences, 4th Floor, Gakkai Center Bldg., 4-16, Yayoi 2-chome, Bunkyo-ku, Tokyo 113, Japan) V.1- 1976- Volume(issue)/page/year: 8(Suppl 1),1,1983