N-methyl-1,2-diphenyl-ethanamine hydrochloride

名称

[ CAS 号 ]:
7400-77-3

[ 英文名 ]:
N-methyl-1,2-diphenyl-ethanamine hydrochloride

[英文别名 ]:

物理化学性质

[ 沸点 ]:
298.6ºC at 760mmHg

[ 分子式 ]:
C15H18ClN

[ 分子量 ]:
247.76300

[ 闪点 ]:
131.3ºC

[ 精确质量 ]:
247.11300

[ PSA ]:
12.03000

[ LogP ]:
4.38270

毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SI0800000
CHEMICAL NAME :
Phenethylamine, N-methyl-alpha-phenyl-, hydrochloride
CAS REGISTRY NUMBER :
7400-77-3
LAST UPDATED :
199112
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C15-H17-N.Cl-H
MOLECULAR WEIGHT :
247.79
WISWESSER LINE NOTATION :
1MYR&1R &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
60 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 77,317,1943
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
443 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - changes in motor activity (specific assay)
REFERENCE :
JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 39,354,1950
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