Yohimban-16-carboxylic acid, 11,17-dimethoxy-18-((tetrahydro-2H-pyran-2-yl)oxy)-, methyl ester, (3beta,16beta,17alpha,18beta,20alpha)- (9CI)

名称

[ CAS 号 ]:
751-73-5

[ 英文名 ]:
Yohimban-16-carboxylic acid, 11,17-dimethoxy-18-((tetrahydro-2H-pyran-2-yl)oxy)-, methyl ester, (3beta,16beta,17alpha,18beta,20alpha)- (9CI)

[英文别名 ]:

Su-7064

物理化学性质

[ 密度 ]:
1.27g/cm3

[ 沸点 ]:
638.9ºC at 760 mmHg

[ 分子式 ]:
C₂₈H₃₈N₂O₆

[ 分子量 ]:
498.61100

[ 闪点 ]:
340.2ºC

[ 精确质量 ]:
498.27300

[ PSA ]:
82.25000

[ LogP ]:
3.76940

[ 折射率 ]:
1.608

毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: ZF9800000

CHEMICAL NAME :: 3-beta,20-alpha-Yohimban-16-beta-carboxylic acid, 11-alpha,17-alpha-dimethoxy-18-beta- (tetrahydro-2-pyranyloxy)-, methyl ester

CAS REGISTRY NUMBER :: 751-73-5

LAST UPDATED :: 199012

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C28-H38-N2-O6

MOLECULAR WEIGHT :: 498.68

WISWESSER LINE NOTATION :: T F6 D5 C666 EM ON&&TTTJ HO1 TO1 UVO1 SO- BT6OTJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 173 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,112,1972

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 7 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,112,1972

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