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L-色氨酸甲酯盐酸盐

L-色氨酸甲酯盐酸盐名称

[ CAS 号 ]:
7524-52-9

[ 中文名 ]:
L-色氨酸甲酯盐酸盐

[ 英文名 ]:
Methyl L-tryptophanate hydrochloride

[中文别名 ]:

色氨酸甲酯HCL

[英文别名 ]:

L-Tryptophan methyl ester hydrochloride
EINECS 231-385-5
MFCD00066134
Methyl L-tryptophanate hydrochloride (1:1)
D-Tryptophan methyl ester hydrochloride
H-Trp-OMe·HCl
L-Tryptophanmethylesterhydrochloridesalt
Methyl L-tryptophanate hydrochloride

L-色氨酸甲酯盐酸盐物理化学性质

[ 沸点 ]:
390.6ºC at 760 mmHg

[ 熔点 ]:
218-220ºC

[ 分子式 ]:
C₁₂H₁₅ClN₂O₂

[ 分子量 ]:
254.713

[ 闪点 ]:
190ºC

[ 精确质量 ]:
254.082199

[ PSA ]:
68.11000

[ LogP ]:
2.71300

[ 外观性状 ]:
白色至灰白色结晶粉末

[ 折射率 ]:
19.5 ° (C=5， MeOH)

[ 储存条件 ]:
存放于惰性气体之中;避免湿气 (分解)

L-色氨酸甲酯盐酸盐MSDS

L-色氨酸甲酯盐酸盐安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi

[ 安全声明 (欧洲) ]:
S22-S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

L-色氨酸甲酯盐酸盐合成路线

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L-色氨酸甲酯盐酸盐文献

Inhibition of indoleamine 2,3-dioxygenase activity by levo-1-methyl tryptophan blocks gamma interferon-induced Chlamydia trachomatis persistence in human epithelial cells.

Infect. Immun. 79 , 4425-4437, (2011)

Gamma interferon (IFN-γ) induces expression of the tryptophan-catabolizing enzyme indoleamine 2,3-dioxygenase (IDO1) in human epithelial cells, the permissive cells for the obligate intracellular bact...

Clinical significance of tryptophan metabolism in the nontumoral hemisphere in patients with malignant glioma.

J. Nucl. Med. 55(10) , 1605-10, (2014)

α-(11)C-methyl-L-tryptophan (AMT) PET allows evaluation of brain serotonin synthesis and can also track upregulation of the immunosuppressive kynurenine pathway in tumor tissue. Increased AMT uptake i...

Transport and signaling via the amino acid binding site of the yeast Gap1 amino acid transceptor.

Nat. Chem. Biol. 5 , 45-52, (2009)

Transporter-related nutrient sensors, called transceptors, mediate nutrient activation of signaling pathways through the plasma membrane. The mechanism of action of transporting and nontransporting tr...

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