acridin-9-yl-(3-methylphenyl)azanium chloride

名称

[ CAS 号 ]:
75651-13-7

[ 英文名 ]:
acridin-9-yl-(3-methylphenyl)azanium chloride

物理化学性质

[ 密度 ]:
1.219g/cm3

[ 沸点 ]:
448.1ºC at 760 mmHg

[ 分子式 ]:
C₂₀H₁₇ClN₂

[ 分子量 ]:
320.81500

[ 闪点 ]:
224.8ºC

[ 精确质量 ]:
320.10800

[ PSA ]:
24.92000

[ LogP ]:
6.31500

[ 折射率 ]:
1.741

毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AR9546400

CHEMICAL NAME :: Acridine, 9-(m-toluidino)-, hydrochloride

CAS REGISTRY NUMBER :: 75651-13-7

LAST UPDATED :: 198609

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C20-H16-N2.Cl-H

MOLECULAR WEIGHT :: 320.84

WISWESSER LINE NOTATION :: T C666 BNJ IMR C1 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD10 - Lethal Dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 375 mg/kg

TOXIC EFFECTS :: Tumorigenic - active as anti-cancer agent

MUTATION DATA

TYPE OF TEST :: DNA damage

TEST SYSTEM :: Mammal - species unspecified Lymphocyte

DOSE/DURATION :: 15 umol/L

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 24,170,1981

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