西诺西泮

西诺西泮用途

Cinolazepam is a benzodiazepine derivative drug. It possesses anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties. Due to its strong sedative properties, it is primarily used as an hypnotic.

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西诺西泮名称

[ CAS 号 ]:
75696-02-5

[ 中文名 ]:
西诺西泮

[ 英文名 ]:
Cinolazepam

[英文别名 ]:

OX-373
Cinolazepam
Cinolazepamum [INN-Latin]
Cinolazepam [INN]
Gerodorm
Gerodorm (TN)
Cinolazepamum

西诺西泮物理化学性质

[ 密度 ]:
1.39g/cm3

[ 沸点 ]:
643.5ºC at 760 mmHg

[ 分子式 ]:
C₁₈H₁₃ClFN₃O₂

[ 分子量 ]:
357.76600

[ 闪点 ]:
343ºC

[ 精确质量 ]:
357.06800

[ PSA ]:
76.69000

[ LogP ]:
2.39578

[ 折射率 ]:
1.646

西诺西泮毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DE9640000

CHEMICAL NAME :: 1H-1,4-Benzodiazepine-1-propanenitrile, 2,3-dihydro-7-chloro-5-(2-fluorophenyl)-2-oxo-

CAS REGISTRY NUMBER :: 75696-02-5

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C18-H13-Cl-F-N3-O2

MOLECULAR WEIGHT :: 357.79

WISWESSER LINE NOTATION :: T67 GNV JN IHJ CG G2CN IQ KR BF

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 7,98,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 3500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 7,98,1982