< 生产厂家价格 >

羟可待酮

羟可待酮名称

[ CAS 号 ]:
76-42-6

[ 中文名 ]:
羟可待酮

[ 英文名 ]:
oxycodone

[中文别名 ]:

[英文别名 ]:

Thecodine
Tekodin
Oxycodon
14-hydroxy-dihydrocodeinone
Oxycon
Oxikon
Eubine
oxanest
Eucodalum
Eukodal

羟可待酮物理化学性质

[ 密度 ]:
1.4±0.1 g/cm3

[ 沸点 ]:
501.6±50.0 °C at 760 mmHg

[ 熔点 ]:
218-220°

[ 分子式 ]:
C₁₈H₂₁NO₄

[ 分子量 ]:
315.364

[ 闪点 ]:
257.1±30.1 °C

[ 精确质量 ]:
315.147064

[ PSA ]:
59.00000

[ LogP ]:
1.67

[ 蒸汽压 ]:
0.0±1.4 mmHg at 25°C

[ 折射率 ]:
1.659

[ 储存条件 ]:
2-8°C

羟可待酮毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QD2450000

CHEMICAL NAME :: Morphinan-6-one, 4,5-alpha-epoxy-14-hydroxy-3-methoxy-17-methyl-

CAS REGISTRY NUMBER :: 76-42-6

BEILSTEIN REFERENCE NO. :: 0043446

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C18-H21-N-O4

MOLECULAR WEIGHT :: 315.40

WISWESSER LINE NOTATION :: T B6566 B6/CO 4ABBC R BX FV HO PN GHT&&TTJ CQ JO1 P1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 320 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 3,261,1961

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 426 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 28ZNAE "Public Health Reports, Supplement." (Washington, DC) Volume(issue)/page/year: 138,27,1938

点击显示

羟可待酮安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302

[ 警示性声明 ]:
P301 + P312 + P330

[ 危害码 (欧洲) ]:
F,T

[ 风险声明 (欧洲) ]:
11-23/24/25-39/23/24/25

[ 安全声明 (欧洲) ]:
7-16-36/37-45

[ 危险品运输编码 ]:
UN 1544

[ 包装等级 ]:
II

[ 危险类别 ]:
6.1(a)

羟可待酮合成路线

详细合成路线

羟可待酮上下游产品

羟可待酮上游产品

羟可待酮下游产品

羟可待酮文献

Inhibition of TRPM8 channels reduces pain in the cold pressor test in humans.

J. Pharmacol. Exp. Ther. 351(2) , 259-69, (2014)

The transient receptor potential (subfamily M, member 8; TRPM8) is a nonselective cation channel localized in primary sensory neurons, and is a candidate for cold thermosensing, mediation of cold pain...

Spontaneous resolution of quadrilateral space syndrome: a case report.

Am. J. Phys. Med. Rehabil. 94(1) , e1-5, (2015)

A case of quadrilateral space syndrome is presented, where a large near-circumferential glenoid labrum tear led to a paralabral cyst that dissected into the quadrilateral space and caused a compressiv...

Rational prescribing.

Minn. Med. 96(3) , 4, (2013)

更多文献