羟可待酮

[ 密度 ]:
1.4±0.1 g/cm3

[ 沸点 ]:
501.6±50.0 °C at 760 mmHg

[ 熔点 ]:
218-220°

[ 分子式 ]:
C₁₈H₂₁NO₄

[ 分子量 ]:
315.364

[ 闪点 ]:
257.1±30.1 °C

[ 精确质量 ]:
315.147064

[ PSA ]:
59.00000

[ LogP ]:
1.67

[ 蒸汽压 ]:
0.0±1.4 mmHg at 25°C

[ 折射率 ]:
1.659

[ 储存条件 ]:
2-8°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :

QD2450000

CHEMICAL NAME :

Morphinan-6-one, 4,5-alpha-epoxy-14-hydroxy-3-methoxy-17-methyl-

CAS REGISTRY NUMBER :

76-42-6

BEILSTEIN REFERENCE NO. :

0043446

LAST UPDATED :

199612

DATA ITEMS CITED :

2

MOLECULAR FORMULA :

C18-H21-N-O4

MOLECULAR WEIGHT :

315.40

WISWESSER LINE NOTATION :

T B6566 B6/CO 4ABBC R BX FV HO PN GHT&&TTJ CQ JO1 P1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

320 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 3,261,1961

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Subcutaneous

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

426 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

28ZNAE "Public Health Reports, Supplement." (Washington, DC) Volume(issue)/page/year: 138,27,1938

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302

[ 警示性声明 ]:
P301 + P312 + P330

[ 危害码 (欧洲) ]:
F,T

[ 风险声明 (欧洲) ]:
11-23/24/25-39/23/24/25

[ 安全声明 (欧洲) ]:
7-16-36/37-45

[ 危险品运输编码 ]:
UN 1544

[ 包装等级 ]:
II

[ 危险类别 ]:
6.1(a)

详细合成路线

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