d-N-Methylchondrodendrine diiodide

d-N-Methylchondrodendrine diiodide名称

[ CAS 号 ]:
76786-15-7

[ 英文名 ]:
d-N-Methylchondrodendrine diiodide

[英文别名 ]:

d-N-Methylchondrodendrine diiodide物理化学性质

[ 分子式 ]:
C38H44I2N2O6

[ 分子量 ]:
878.57500

[ 精确质量 ]:
878.12900

[ PSA ]:
83.04000

[ LogP ]:
9.63600

d-N-Methylchondrodendrine diiodide毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YO3688000
CHEMICAL NAME :
Tubocuraranium, 7',12'-dihydroxy-6,6'-dimethoxy-2,2,2',2'-tetramethyl -, diiodide, (1'-alpha)-
CAS REGISTRY NUMBER :
76786-15-7
LAST UPDATED :
198910
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C38-H44-N2-O6.2I
MOLECULAR WEIGHT :
878.64

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Human - man
DOSE/DURATION :
600 ug/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - ptosis Vascular - BP lowering not characterized in autonomic section Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 93,109,1948
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
550 ug/kg
TOXIC EFFECTS :
Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 93,109,1948
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
400 ug/kg
TOXIC EFFECTS :
Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 93,109,1948
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