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Ebelactone A

Ebelactone A名称

[ CAS 号 ]:
76808-16-7

[ 英文名 ]:
Ebelactone A

[英文别名 ]:

ebelactone a microbial

Ebelactone A物理化学性质

[ 密度 ]:
1.011g/cm3

[ 沸点 ]:
462.8ºC at 760 mmHg

[ 分子式 ]:
C₂₀H₃₄O₄

[ 分子量 ]:
338.48200

[ 闪点 ]:
152.8ºC

[ 精确质量 ]:
338.24600

[ PSA ]:
63.60000

[ LogP ]:
3.76870

[ 折射率 ]:
1.483

Ebelactone AMSDS

详细MSDS(安全技术说明书)

Ebelactone A毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: RQ7730000

CHEMICAL NAME :: 2-Oxetanone, 4-(8-hydroxy-1,3,5,7,9-pentamethyl-6-oxo-3-undecenyl) -3-methyl-, (3S-(3- alpha,4-beta(1R*,3E,5S*,7R*,8S*,9S*)))-

CAS REGISTRY NUMBER :: 76808-16-7

LAST UPDATED :: 199712

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C20-H34-O4

MOLECULAR WEIGHT :: 338.54

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >250 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 33,1594,1980

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Ebelactone A安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
RQ7730000

Ebelactone A文献

Structural studies on ebelactone A and B, esterase inhibitors produced by actinomycetes.

J. Antibiot. 35 , 1495-1499, (1982)

Biosynthetic studies of ebelactone A and B by 13C NMR spectrometry.

J. Antibiot. 35 , 1670, (1982)

Biosynthetic pathways of ebelactone A and B were studied by 13C NMR spectroscopy. By using 13C labeled compounds as precursors it was determined that ebelactone A was derived from one molecule of acet...

Effects of ebelactone B, a lipase inhibitor, on intestinal fat absorption in the rat.

J. Enzym. Inhib. 10(1) , 57-63, (1996)

Ebelactones A and B, natural products from Streptomyces aburaviensis are potent inhibitors of pancreatic lipase. Lipase is the key enzyme required for the absorption of dietary triglycerides (TG). Ebe...

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