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对硝基苯基氯甲酸酯

对硝基苯基氯甲酸酯用途

【用途一】
核苷类的羟基及氨基保护试剂，有机合成、医药合成中间体，可用于合成利托那韦（治疗艾滋病药物，蛋白酶抑制剂）。

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对硝基苯基氯甲酸酯名称

[ CAS 号 ]:
7693-46-1

[ 中文名 ]:
对硝基苯基氯甲酸酯

[ 英文名 ]:
4-Nitrophenyl chloroformate

[中文别名 ]:

[英文别名 ]:

Nitrophenyl chloroforMate
4-Nitrophenyl Chlorooate
4-nitrophenoxycarbonyl chloride
Carbonochloridic acid, 4-nitrophenyl ester
P-NITROPHENYL CHLOROCARBONATE
4-Nitrophenyl chloroformate
p-nitrophenyloxycarbonyl chloride
chloroformic acid 4-nitrophenyl ester
chlorocarbonic acid p-nitrophenyl ester
4-Nitrophenylchlorocarbonat

对硝基苯基氯甲酸酯物理化学性质

[ 密度 ]:
1.5±0.1 g/cm3

[ 沸点 ]:
283.6±13.0 °C at 760 mmHg

[ 熔点 ]:
77-79 °C(lit.)

[ 分子式 ]:
C₇H₄ClNO₄

[ 分子量 ]:
201.564

[ 闪点 ]:
125.3±19.8 °C

[ 精确质量 ]:
200.982880

[ PSA ]:
72.12000

[ LogP ]:
2.84

[ 外观性状 ]:
奶油色固体

[ 蒸汽压 ]:
0.0±0.6 mmHg at 25°C

[ 折射率 ]:
1.577

[ 储存条件 ]:
2-8°C

[ 稳定性 ]:
Stable. Incompatible with strong bases, acids. Combustible.

[ 水溶解性 ]:
decomposes

对硝基苯基氯甲酸酯MSDS

对硝基苯基氯甲酸酯安全信息

[ 符号 ]:

GHS05, GHS07

[ 信号词 ]:
Danger

[ 危害声明 ]:
H314-H335

[ 警示性声明 ]:
P261-P280-P305 + P351 + P338-P310

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ 危害码 (欧洲) ]:
C:Corrosive

[ 风险声明 (欧洲) ]:
R23/24/25;R34

[ 安全声明 (欧洲) ]:
S26-S36/37/39-S45-S38-S28A-S36-S16

[ 危险品运输编码 ]:
UN 3261 8/PG 2

[ WGK德国 ]:
3

[ 包装等级 ]:
II

[ 危险类别 ]:
8

[ 海关编码 ]:
29159020

对硝基苯基氯甲酸酯合成路线

对硝基苯基氯甲酸酯上下游产品

对硝基苯基氯甲酸酯上游产品

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对硝基苯基氯甲酸酯海关

[ 海关编码 ]: 2915900090

[ 中文概述 ]:
2915900090. 其他饱和无环一元羧酸及其酸酐（酰卤、过氧）化物、过氧酸及其卤化、硝化、磺化、亚硝化衍生物. 增值税率:17.0%. 退税率:9.0%. 监管条件:AB(入境货物通关单,出境货物通关单). 最惠国关税:5.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ 监管条件 ]: A.入境货物通关单 B.出境货物通关单

[ 检验检疫 ]: R.进口食品卫生监督检验 S.出口食品卫生监督检验 M.进口商品检验 N.出口商品检验

[ Summary ]:
2915900090 other saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:5.5% General tariff:30.0%

对硝基苯基氯甲酸酯文献

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