Maytansine, O3-acetyl-O3-de2-(acetylmethylamino)-1-oxopropyl-22-demethyl-
名称
[ CAS 号 ]:
77353-67-4
[ 英文名 ]:
Maytansine, O3-acetyl-O3-de2-(acetylmethylamino)-1-oxopropyl-22-demethyl-
[英文别名 ]:
物理化学性质
[ 密度 ]:
1.34g/cm3
[ 沸点 ]:
789ºC at 760 mmHg
[ 分子式 ]:
C29H37ClN2O9
[ 分子量 ]:
593.06500
[ 闪点 ]:
431ºC
[ 精确质量 ]:
592.21900
[ PSA ]:
151.93000
[ LogP ]:
3.38830
[ 折射率 ]:
1.592
毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- OQ2290500
- CHEMICAL NAME :
- Maytansine, O(sup 3)-acetyl-O(sup 3)-de(2-(acetylmethylamino)-1-oxopropyl)-22-demethyl-
- CAS REGISTRY NUMBER :
- 77353-67-4
- LAST UPDATED :
- 199207
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C29-H37-Cl-N2-O9
- MOLECULAR WEIGHT :
- 593.13
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2500 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- EPXXDW European Patent Application. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #25898
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JKXXAF Japanese Kokai Tokyo Koho Patents. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #80-118490
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相关化合物
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