Piperazine, 1,4-bis[ (2, 3-dihydro-1,4-benzodioxin-2-yl)methyl]-
名称
[ CAS 号 ]:
7762-32-5
[ 英文名 ]:
Piperazine, 1,4-bis[ (2, 3-dihydro-1,4-benzodioxin-2-yl)methyl]-
[英文别名 ]:
- dibozane
- Dibozan
- MCN-181
物理化学性质
[ 密度 ]:
1.223g/cm3
[ 沸点 ]:
513.6ºC at 760 mmHg
[ 分子式 ]:
C22H26N2O4
[ 分子量 ]:
382.45300
[ 闪点 ]:
147ºC
[ 精确质量 ]:
382.18900
[ PSA ]:
43.40000
[ LogP ]:
2.15980
[ 折射率 ]:
1.586
毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TK8750000
- CHEMICAL NAME :
- Piperazine, 1,4-bis(1,4-benzodioxan-2-ylmethyl)-
- CAS REGISTRY NUMBER :
- 7762-32-5
- LAST UPDATED :
- 199012
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C22-H26-N2-O4
- MOLECULAR WEIGHT :
- 382.50
- WISWESSER LINE NOTATION :
- T66 BO EOJ C1- AT6N DNTJ D1- CT66 BO EOJ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 600 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JMPCAS Journal of Medicinal and Pharmaceutical Chemistry. (Washington, DC) V.1-5, 1959-62. For publisher information, see JMCMAR. Volume(issue)/page/year: 5,1285,1962
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 50 mg/kg
- TOXIC EFFECTS :
- Behavioral - muscle weakness Lungs, Thorax, or Respiration - respiratory depression Gastrointestinal - changes in structure or function of salivary glands
- REFERENCE :
- FEPRA7 Federation Proceedings, Federation of American Societies for Experimental Biology. (Bethesda, MD) V.1-46, 1942-87. Volume(issue)/page/year: 12,355,1953
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 43 mg/kg
- TOXIC EFFECTS :
- Behavioral - muscle weakness Lungs, Thorax, or Respiration - respiratory depression Gastrointestinal - changes in structure or function of salivary glands
- REFERENCE :
- FEPRA7 Federation Proceedings, Federation of American Societies for Experimental Biology. (Bethesda, MD) V.1-46, 1942-87. Volume(issue)/page/year: 12,355,1953
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