Piperazine, 1,4-bis[ (2, 3-dihydro-1,4-benzodioxin-2-yl)methyl]-

名称

[ CAS 号 ]:
7762-32-5

[ 英文名 ]:
Piperazine, 1,4-bis[ (2, 3-dihydro-1,4-benzodioxin-2-yl)methyl]-

[英文别名 ]:

物理化学性质

[ 密度 ]:
1.223g/cm3

[ 沸点 ]:
513.6ºC at 760 mmHg

[ 分子式 ]:
C22H26N2O4

[ 分子量 ]:
382.45300

[ 闪点 ]:
147ºC

[ 精确质量 ]:
382.18900

[ PSA ]:
43.40000

[ LogP ]:
2.15980

[ 折射率 ]:
1.586

毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TK8750000
CHEMICAL NAME :
Piperazine, 1,4-bis(1,4-benzodioxan-2-ylmethyl)-
CAS REGISTRY NUMBER :
7762-32-5
LAST UPDATED :
199012
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C22-H26-N2-O4
MOLECULAR WEIGHT :
382.50
WISWESSER LINE NOTATION :
T66 BO EOJ C1- AT6N DNTJ D1- CT66 BO EOJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JMPCAS Journal of Medicinal and Pharmaceutical Chemistry. (Washington, DC) V.1-5, 1959-62. For publisher information, see JMCMAR. Volume(issue)/page/year: 5,1285,1962
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
50 mg/kg
TOXIC EFFECTS :
Behavioral - muscle weakness Lungs, Thorax, or Respiration - respiratory depression Gastrointestinal - changes in structure or function of salivary glands
REFERENCE :
FEPRA7 Federation Proceedings, Federation of American Societies for Experimental Biology. (Bethesda, MD) V.1-46, 1942-87. Volume(issue)/page/year: 12,355,1953
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
43 mg/kg
TOXIC EFFECTS :
Behavioral - muscle weakness Lungs, Thorax, or Respiration - respiratory depression Gastrointestinal - changes in structure or function of salivary glands
REFERENCE :
FEPRA7 Federation Proceedings, Federation of American Societies for Experimental Biology. (Bethesda, MD) V.1-46, 1942-87. Volume(issue)/page/year: 12,355,1953
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相关化合物

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