Glycine,N-(2-diazoacetyl)-, hydrazide
Glycine,N-(2-diazoacetyl)-, hydrazide名称
[ CAS 号 ]:
820-75-7
[ 英文名 ]:
Glycine,N-(2-diazoacetyl)-, hydrazide
[英文别名 ]:
- N-Diazoacetyl glycylhydrazide
- N-Diazoacetilglicina-idrazide
- N-Diazoacetyl glycyclhydrazide
- N-Diazoacetyl-glycin-hydrazid
- N-Diazoacetylglycine hydrazide
- Diazoacetylglycine hydrazide
- Diazoacetyl-aminoessigsaeurehydrazid
Glycine,N-(2-diazoacetyl)-, hydrazide物理化学性质
[ 分子式 ]:
C4H7N5O2
[ 分子量 ]:
157.13100
[ 精确质量 ]:
157.06000
[ PSA ]:
121.61000
Glycine,N-(2-diazoacetyl)-, hydrazide毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- MB9450000
- CHEMICAL NAME :
- Glycine, N-(diazoacetyl)-, hydrazide
- CAS REGISTRY NUMBER :
- 820-75-7
- LAST UPDATED :
- 199703
- DATA ITEMS CITED :
- 17
- MOLECULAR FORMULA :
- C4-H7-N5-O2
- MOLECULAR WEIGHT :
- 157.16
- WISWESSER LINE NOTATION :
- ZMV1UNN
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1335 mg/kg
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - emphysema Behavioral - muscle contraction or spasticity Gastrointestinal - hypermotility, diarrhea
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1595 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - cyanosis Lungs, Thorax, or Respiration - other changes
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 3852 mg/kg
- TOXIC EFFECTS :
- Gastrointestinal - other changes
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2575 mg/kg
- TOXIC EFFECTS :
- Gastrointestinal - other changes Liver - other changes Kidney, Ureter, Bladder - other changes
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2985 mg/kg
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - emphysema Cardiac - other changes Gastrointestinal - other changes
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 39 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - dyspnea Gastrointestinal - nausea or vomiting
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 833 mg/kg
- TOXIC EFFECTS :
- Behavioral - muscle weakness Lungs, Thorax, or Respiration - dyspnea Lungs, Thorax, or Respiration - respiratory depression
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2100 mg/kg/7D-I
- TOXIC EFFECTS :
- Liver - hepatitis (hepatocellular necrosis), zonal Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Blood - changes in bone marrow (not otherwise specified)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2100 mg/kg/7D-I
- TOXIC EFFECTS :
- Endocrine - changes in spleen weight Blood - changes in bone marrow (not otherwise specified) Blood - changes in erythrocyte (RBC) count
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 780 mg/kg/20D-I
- TOXIC EFFECTS :
- Gastrointestinal - alteration in gastric secretion Blood - hemorrhage Blood - changes in bone marrow (not otherwise specified)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 1080 mg/kg/10D-I
- TOXIC EFFECTS :
- Behavioral - food intake (animal) Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Kidney, Ureter, Bladder - proteinuria
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1200 mg/kg/4D-I
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Lungs, Thorax, or Respiration - tumors Blood - leukemia
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 720 mg/kg/4D-I
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria Lungs, Thorax, or Respiration - tumors Blood - leukemia
MUTATION DATA
- TYPE OF TEST :
- Unscheduled DNA synthesis
- TEST SYSTEM :
- Rodent - mouse Fibroblast
- DOSE/DURATION :
- 2500 umol/L
- REFERENCE :
- JCROD7 Journal of Cancer Research and Clinical Oncology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.93- 1979- Volume(issue)/page/year: 94,7,1979
点击显示
Glycine,N-(2-diazoacetyl)-, hydrazide合成路线
Glycine,N-(2-diazoacetyl)-, hydrazide上下游产品
Glycine,N-(2-diazoacetyl)-, hydrazide上游产品
Glycine,N-(2-diazoacetyl)-, hydrazide下游产品
推荐生产厂家/供应商：
暂无推荐供应商。请联系客服获知如何成为推荐供应商。
相关化合物
[Glycine,N-(2-diazoacetyl)-, hydrazide]化源网提供Glycine,N-(2-diazoacetyl)-, hydrazideCAS号820-75-7，Glycine,N-(2-diazoacetyl)-, hydrazideMSDS及其说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。CAS号查询Glycine,N-(2-diazoacetyl)-, hydrazide上化源网，专业又轻松。>>电脑版：Glycine,N-(2-diazoacetyl)-, hydrazide
标题：820-75-7_Glycine,N-(2-diazoacetyl)-, hydrazideCAS号:820-75-7_Glycine,N-(2-diazoacetyl)-, hydrazide【结构式 性质 英文】 - 化源网 地址：https://m.chemsrc.com/mip/cas/820-75-7_449294.html