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5,6-二氢-苯并[c]吖啶-7-羧酸

5,6-二氢-苯并[c]吖啶-7-羧酸名称

[ CAS 号 ]:
83-93-2

[ 中文名 ]:
5,6-二氢-苯并[c]吖啶-7-羧酸

[ 英文名 ]:
5,6-DIHYDRO-BENZO[C]ACRIDINE-7-CARBOXYLIC ACID

[英文别名 ]:

Tetrophan
Tetrofan
5,6-dihydrobenz<c>acridine-7-carboxylic acid
3,4-Dihydro-1,2-benzacridinic-5-carbonic acid

5,6-二氢-苯并[c]吖啶-7-羧酸物理化学性质

[ 密度 ]:
1.336g/cm3

[ 沸点 ]:
495.8ºC at 760 mmHg

[ 分子式 ]:
C₁₈H₁₃NO₂

[ 分子量 ]:
275.30100

[ 闪点 ]:
253.7ºC

[ 精确质量 ]:
275.09500

[ PSA ]:
50.19000

[ LogP ]:
3.69860

[ 折射率 ]:
1.719

5,6-二氢-苯并[c]吖啶-7-羧酸毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CU3350000

CHEMICAL NAME :: Benz(c)acridine-7-carboxylic acid, 5,6-dihydro-

CAS REGISTRY NUMBER :: 83-93-2

BEILSTEIN REFERENCE NO. :: 0256492

LAST UPDATED :: 199709

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C18-H13-N-O2

MOLECULAR WEIGHT :: 275.32

WISWESSER LINE NOTATION :: T D6 C666 BN&T&&J MVQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 760 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 113,27,1955

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Mammal - cat

DOSE/DURATION :: 40 mg/kg

TOXIC EFFECTS :: Vascular - BP lowering not characterized in autonomic section

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 113,27,1955

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 40 mg/kg

TOXIC EFFECTS :: Behavioral - tetany Cardiac - other changes Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 113,371,1955

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5,6-二氢-苯并[c]吖啶-7-羧酸安全信息

[ 海关编码 ]:
2933990090

5,6-二氢-苯并[c]吖啶-7-羧酸合成路线

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5,6-二氢-苯并[c]吖啶-7-羧酸上下游产品

5,6-二氢-苯并[c]吖啶-7-羧酸上游产品

5,6-二氢-苯并[c]吖啶-7-羧酸下游产品

5,6-二氢-苯并[c]吖啶-7-羧酸海关

[ 海关编码 ]: 2933990090

[ 中文概述 ]:
2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%