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MDL72274 HCl

MDL72274 HCl用途

MDL-72274 HCl is selective and potent inhibitors of SSAO for treatment of Parkinson diseases. MDL-72974 is a potent (IC50 = 10(-9) M) inhibitor of both MAO-B and SSAO, with 190-fold lower affinity for MAO-A. In clinical studies, oral doses as low as 100 micrograms produced substantial inhibition of platelet MAO-B. One or 4 mg MDL-72274 HCl given daily for 28 days to 40 Parkinson's patients treated with L-dopa produced statistically significant reductions in the Unified Parkinson's Disease Rating Scale. MAO-B inhibitors, such as MDL 72974A and L-deprenyl, offer the potential of being neuroprotective in Parkinson's Disease and other neurogenerative disorders.
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MDL72274 HCl名称

[ CAS 号 ]:
85278-24-6

[ 英文名 ]:
MDL72274 HCl

[英文别名 ]:

MDL72274 HCl物理化学性质

[ 分子式 ]:
C9H11Cl2N

[ 分子量 ]:
204.09600

[ 精确质量 ]:
203.02700

[ PSA ]:
26.02000

[ LogP ]:
3.72730

推荐生产厂家/供应商：

公司名：上海源溪生物科技有限公司

区域：上海市浦东新区

价格：
￥需询单/1g

联系人：赖经理

产品详情：MDL72274

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MDL72274 HCl供应商

相关化合物

[MDL72274 HCl]化源网提供MDL72274 HClCAS号85278-24-6，MDL72274 HClMSDS及其说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。CAS号查询MDL72274 HCl上化源网，专业又轻松。>>电脑版：MDL72274 HCl

标题：85278-24-6_MDL72274 HClCAS号:85278-24-6_MDL72274 HCl【结构式 性质 英文】 - 化源网 地址：https://m.chemsrc.com/mip/cas/85278-24-6_1396520.html