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(5α,17β)-3-Oxoandrostan-17-yl propionate

名称

[ CAS 号 ]:
855-22-1

[ 英文名 ]:
(5α,17β)-3-Oxoandrostan-17-yl propionate

[英文别名 ]:

物理化学性质

[ 密度 ]:
1.08g/cm3

[ 沸点 ]:
438ºC at 760 mmHg

[ 分子式 ]:
C22H34O3

[ 分子量 ]:
346.50400

[ 闪点 ]:
188ºC

[ 精确质量 ]:
346.25100

[ PSA ]:
43.37000

[ LogP ]:
4.92000

[ 折射率 ]:
1.524

毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :
BV8071500
CHEMICAL NAME :
5-alpha-Androstan-3-one, 17-beta-hydroxy-, propionate
CAS REGISTRY NUMBER :
855-22-1
BEILSTEIN REFERENCE NO. :
2628403
LAST UPDATED :
199612
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C22-H34-O3
MOLECULAR WEIGHT :
346.56
WISWESSER LINE NOTATION :
L E5 B666 OVTJ A1 E1 FOV2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
50 ug/kg
SEX/DURATION :
female 1 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Maternal Effects - ovaries, fallopian tubes Reproductive - Maternal Effects - uterus, cervix, vagina
REFERENCE :
JRPFA4 Journal of Reproduction and Fertility. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1960- Volume(issue)/page/year: 30,55,1972
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
20 mg/kg
SEX/DURATION :
female 4 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Fertility - other measures of fertility
REFERENCE :
BIREBV Biology of Reproduction. (Soc. for the Study of Reproduction, 309 W. Clark St., Champaign, IL 61820) V.1- 1969- Volume(issue)/page/year: 20,384,1979
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
3 gm/kg
SEX/DURATION :
male 6 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Paternal Effects - testes, epididymis, sperm duct Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland, accessory glands
REFERENCE :
JOENAK Journal of Endocrinology. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1939- Volume(issue)/page/year: 51,241,1971
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
150 mg/kg
SEX/DURATION :
female 28-58 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Newborn - delayed effects
REFERENCE :
HOBEAO Hormones and Behavior. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1969- Volume(issue)/page/year: 6,139,1975
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Implant
DOSE :
208 mg/kg
SEX/DURATION :
male 82 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Paternal Effects - testes, epididymis, sperm duct Reproductive - Paternal Effects - other effects on male
REFERENCE :
JRPFA4 Journal of Reproduction and Fertility. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1960- Volume(issue)/page/year: 94,57,1992
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