N-亚硝基二苯胺
N-亚硝基二苯胺用途
用作天然橡胶、合成橡胶(丁基橡胶除外)的防焦剂，也可作为已有轻微焦烧的胶料的再塑化剂，还可作高效阻聚剂
【用途二】
用作天然橡胶、合成橡胶（丁基橡胶除外）了防焦剂，也可作为已有轻微焦烧的胶料的再塑化剂。可代替木焦油作为氯丁橡胶的高效阴聚剂。是防老剂4010和染料的中间体。
【用途三】
工业上用作天然橡胶、合成橡胶（丁基橡胶除外）了防焦剂，也可作为已有轻微焦烧的胶料的再塑化剂。可代替木焦油作为氯丁橡胶的高效阴聚剂。是防老剂4010和染料的中间体。
【用途四】
用作天然橡胶，合成橡胶(丁基橡胶除外)了防焦剂，也可作为已有轻微焦烧的胶料的再塑化剂。可代替木焦油作为氯丁橡胶的高效阴聚剂。是防老剂4010和染料的中间体。
N-亚硝基二苯胺名称
[ CAS 号 ]:
86-30-6
[ 中文名 ]:
N-亚硝基二苯胺
[ 英文名 ]:
N-NITROSO-DIPHENYLAMINE
[中文别名 ]:
[英文别名 ]:
- N-NITROSO-DIPHENYLAMINE
- Ndpa
- Ortard
- NdphA
- N-Nitroso-N-phenylaniline
- Sconoc
- TJB
- MFCD00019920
- Vultrol
- Benzenamine, N-nitroso-N-phenyl-
N-亚硝基二苯胺物理化学性质
[ 密度 ]:
1.1±0.1 g/cm3
[ 沸点 ]:
346.5±15.0 °C at 760 mmHg
[ 熔点 ]:
65-66 °C
[ 分子式 ]:
C12H10N2O
[ 分子量 ]:
198.221
[ 闪点 ]:
163.4±20.4 °C
[ 精确质量 ]:
198.079315
[ PSA ]:
32.67000
[ LogP ]:
3.13
[ 外观性状 ]:
橙色至棕色固体
[ 蒸汽压 ]:
0.0±0.8 mmHg at 25°C
[ 折射率 ]:
1.582
[ 储存条件 ]:
库房通风低温干燥,与氧化剂、食品添加剂分开存放
[ 稳定性 ]:
Stability Combustible. Incompatible with oxidising agents.
[ 水溶解性 ]:
Insoluble
N-亚硝基二苯胺MSDS
N-亚硝基二苯胺毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- JJ9800000
- CHEMICAL NAME :
- Diphenylamine, N-nitroso-
- CAS REGISTRY NUMBER :
- 86-30-6
- BEILSTEIN REFERENCE NO. :
- 0909531
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 59
- MOLECULAR FORMULA :
- C12-H10-N2-O
- MOLECULAR WEIGHT :
- 198.24
- WISWESSER LINE NOTATION :
- ONNR&R
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1825 mg/kg
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - cyanosis
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 3 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1860 mg/kg
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - cyanosis
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- >7940 mg/kg
- TOXIC EFFECTS :
- Behavioral - food intake (animal) Behavioral - changes in motor activity (specific assay)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 2440 mg/kg/17W-I
- TOXIC EFFECTS :
- Nutritional and Gross Metabolic - weight loss or decreased weight gain
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 140 gm/kg/2Y-C
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Kidney, Ureter, Bladder - tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 800 mg/kg/20W-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - bronchiogenic carcinoma Tumorigenic - increased incidence of tumors in susceptible strains
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 170 gm/kg/2Y-C
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Kidney, Ureter, Bladder - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2800 gm/kg/2Y-C
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Kidney, Ureter, Bladder - tumors Skin and Appendages - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 800 mg/kg/20W-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 7700 mg/kg/77W-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors Endocrine - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1750 gm/kg/2Y-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Kidney, Ureter, Bladder - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 146 gm/kg/2Y-C
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Kidney, Ureter, Bladder - tumors
- TYPE OF TEST :
- Specific locus test
MUTATION DATA
- TYPE OF TEST :
- Sister chromatid exchange
- TEST SYSTEM :
- Rodent - hamster Fibroblast
- DOSE/DURATION :
- 100 umol/L
- REFERENCE :
- JNCIAM Journal of the National Cancer Institute. (Washington, DC) V.1-60, 1940-78. For publisher information, see JJIND8. Volume(issue)/page/year: 58,1635,1977 *** REVIEWS *** IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 27,213,1982 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 27,213,1982 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 82865 No. of Facilities: 102 (estimated) No. of Industries: 3 No. of Occupations: 19 No. of Employees: 3163 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 82865 No. of Facilities: 137 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 1093 (estimated)
N-亚硝基二苯胺安全信息
[ 符号 ]:
GHS06, GHS08
[ 信号词 ]:
Danger
[ 危害声明 ]:
H301 + H311 + H331-H370
[ 警示性声明 ]:
P260-P280-P301 + P310-P311
[ 危害码 (欧洲) ]:
Xn: Harmful;
[ 风险声明 (欧洲) ]:
R22
[ 安全声明 (欧洲) ]:
S22-S36/37-S53-S45-S16-S7
[ 危险品运输编码 ]:
UN 1230 3/PG 2
[ WGK德国 ]:
3
[ RTECS号 ]:
JJ9800000
[ 危险类别 ]:
3.0
[ 海关编码 ]:
2928000090
N-亚硝基二苯胺制备
1、由二苯胺与亚硝酸钠在硫酸存在下反应得：亚硝化反应以乙醇或二甲苯（或氯苯）为溶剂，亚硝酸钠溶液含量为40%，浓硫酸含量为30%，在26℃左右反应2.5-3h。反应产物水洗至PH值6-7。当采用乙醇为溶剂时，烘干后得到固体产品；当采用二甲苯或氯苯为溶剂时，获得液体产物，产物需用氯化钙干燥。
2、苯胺以无水三氯化铝为催化剂，进行缩合反应。反应产物经盐酸沿析、氢氧化钠中合、煮洗、真空蒸馏、用乙醇结晶、分离即得成品。
N-亚硝基二苯胺海关
[ 海关编码 ]: 2928000090
[ 中文概述 ]:
2928000090 其他肼（联氨）及胲（羟胺）的有机衍生物。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:6.5%。普通关税:20.0%
[ 申报要素 ]: 品名, 成分含量, 用途
[ Summary ]:
2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%
N-亚硝基二苯胺文献
Biomed Res. Int. 2014 , 817019, (2014)
Millions of people are exposed daily to N-nitrosamines from different environmental sources. The present study aims at investigating the role of N-nitrosamines in the alteration of homocysteine, lipid...
A salting out-acetonitrile homogeneous extraction coupled with gas chromatography-mass spectrometry method for the simultaneous determination of thirteen N-nitrosamines in skin care cosmetics.J. Chromatogr. A. 1422 , 82-8, (2015)
A sensitive gas chromatography-mass spectrometry method was established for the simultaneous determination of thirteen N-nitrosamines (NAs) in skin care cosmetics. The cosmetics samples were firstly d...
A novel method for the identification of inorganic and organic gunshot residue particles of lead-free ammunitions from the hands of shooters using scanning laser ablation-ICPMS and Raman micro-spectroscopy.Analyst 139(23) , 6232-41, (2014)
A method based on scanning laser ablation and inductively coupled plasma-mass spectrometry (SLA-ICPMS) and Raman micro-spectroscopy for the detection and identification of compounds consistent with gu...
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价格：
￥148.0/25g
￥428.0/100g
联系人：刘佳
产品详情：亚硝基二苯胺
公司名：上海阿拉丁生化科技股份有限公司
区域：上海市浦东新区
价格：
￥369.0/100mg
￥需询单/1g
￥需询单/1g
￥需询单/1g
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标题：N-亚硝基二苯胺_MSDS_用途_密度_CAS号【86-30-6】_化源网 地址：https://m.chemsrc.com/mip/cas/86-30-6_749518.html