U-62066

U-62066用途

Spiradoline (U 62066) is a potent, highly selective κ-opioid agonist that has analgesic diuretic and antitussive effects..

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U-62066名称

[ CAS 号 ]:
87151-85-7

[ 英文名 ]:
U-62066

[英文别名 ]:

spiradoline

U-62066物理化学性质

[ 分子式 ]:
C₂₂H₃₀Cl₂N₂O₂

[ 分子量 ]:
425.39200

[ 精确质量 ]:
424.16800

[ PSA ]:
32.78000

[ LogP ]:
4.49830

U-62066MSDS

详细MSDS(安全技术说明书)

U-62066安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

U-62066文献

Early role of the κ opioid receptor in ethanol-induced reinforcement.

Physiol. Behav. 105(5) , 1231-41, (2012)

Effects of early ethanol exposure on later ethanol intake emphasize the importance of understanding the neurobiology of ethanol-induced reinforcement early in life. Infant rats exhibit ethanol-induced...

Characterization of intraocular pressure responses of the Tibetan monkey (Macaca thibetana).

Mol. Vis. 17 , 1405-13, (2011)

To characterize the effects of circadian rhythm, feeding time, age, general anesthesia, and ocular hypotensive compounds on intraocular pressure (IOP) of the Tibetan monkey (Macaca thibetana).Tibetan ...

Pharmacological characterization of 2-methyl-N-((2'-(pyrrolidin-1-ylsulfonyl)biphenyl-4-yl)methyl)propan-1-amine (PF-04455242), a high-affinity antagonist selective for κ-opioid receptors.

J. Pharmacol. Exp. Ther. 339 , 555-566, (2011)

2-Methyl-N-((2'-(pyrrolidin-1-ylsulfonyl)biphenyl-4-yl)methyl)propan-1-amine (PF-04455242) is a novel κ-opioid receptor (KOR) antagonist with high affinity for human (3 nM), rat (21 nM), and mouse (22...

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