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棕榈酰-CYS((RS)-2,3-二(棕榈酰氧基)-丙基)-OH

用途

Pam3 Cys OH是一种合成细菌脂蛋白[1]。

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名称

[ CAS 号 ]:
87420-41-5

[ 中文名 ]:
棕榈酰-CYS((RS)-2,3-二(棕榈酰氧基)-丙基)-OH

[ 英文名 ]:
N-ALPHA-PALMITOYL-S-[2,3-BIS(PALMITOYLOXY)-(2RS)-PROPYL]-L-CYSTEINE

[英文别名 ]:

MFCD00153468

生物活性

[ 描述 ]:

Pam3 Cys OH是一种合成细菌脂蛋白[1]。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[参考文献]

[1]. Hasegawa M, et al. Transitions in oral and intestinal microflora composition and innate immune receptor-dependent stimulation during mouse development. Infect Immun. 2010 Feb;78(2):639-50.

物理化学性质

[ 密度 ]:
0.966g/cm3

[ 沸点 ]:
907.8ºC at 760 mmHg

[ 分子式 ]:
C₅₄H₁₀₃NO₇S

[ 分子量 ]:
910.46300

[ 闪点 ]:
502.8ºC

[ 精确质量 ]:
909.74600

[ PSA ]:
144.30000

[ LogP ]:
16.57880

[ 折射率 ]:
1.482

[ 储存条件 ]:
室温，密封，干燥

MSDS

详细MSDS(安全技术说明书)

安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

文献

Chronic pulmonary LPS tolerance induces selective immunosuppression while maintaining the neutrophilic response.

Shock 33(2) , 162-9, (2010)

LPS challenge causes potent activation of innate immunity. Because LPS is ubiquitously present in ambient air, repeated inhalation may lead to activation of the pulmonary immune response. If this acti...

Attenuated pathogenesis of polymicrobial peritonitis in mice after TLR2 agonist pre-treatment involves ST2 up-regulation.

Int. Immunol. 17(8) , 1035-46, (2005)

The innate immune system uses Toll-like receptors (TLRs) to activate and instruct immune responses against microbial pathogens. Administration of TLR agonists to mice induces a state of hyporesponsive...

Improved intranasal immunization with live-attenuated measles virus after co-inoculation of the lipopeptide MALP-2.

Vaccine 23(39) , 4721-6, (2005)

The macrophage-activating lipopeptide with a molecular weight of 2kDa (MALP-2) activates antigen presenting cells of human, mouse and rat origin in vitro and in vivo. Here, we demonstrate that MALP-2 ...

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