Ecotin, E. coli

Ecotin，| E。大肠杆菌是凝血酶原（丝​​氨酸蛋白酶）的强效广谱抑制剂。该化合物表现出皮摩尔结合常数，用于抑制胰凝乳蛋白酶，弹性蛋白酶，X因子（因子Xa），XII因子（因子XIIa），激肽释放酶和胰蛋白酶。Ecotin，| E。大肠杆菌也可作为MMP（胶原酶）的有效抑制剂，通过结合皮摩尔范围内的胰蛋白酶发挥生物学活性。大肠杆菌Ecotin是粒酶B的抑制剂。 Ecotin,|E. coli|is a strong broad range inhibitor of prothrombin (serine proteases). The compound exhibits picomolar binding constant for the inhibition of chymotrypsin, elastase, Factor X(Factor Xa), Factor XII(Factor XIIa), kallikrein, and trypsin. Ecotin,|E. coli|also acts as an effective inhibitor of MMP(collagenase), and exhibits biological activity by binding trypsin in the picomolar range. Ecotin, E. coli is an inhibitor of granzyme B.