11,12-dimethyl-15,16-dihydrocyclopenta[a]phenanthren-17-one
名称
[ CAS 号 ]:
894-52-0
[ 英文名 ]:
11,12-dimethyl-15,16-dihydrocyclopenta[a]phenanthren-17-one
物理化学性质
[ 分子式 ]:
C19H16O
[ 分子量 ]:
260.33000
[ 精确质量 ]:
260.12000
[ PSA ]:
17.07000
[ LogP ]:
4.73870
毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- GY5715000
- CHEMICAL NAME :
- Cyclopenta(a)phenanthren-17-one, 15,16-dihydro-11,12-dimethyl-
- CAS REGISTRY NUMBER :
- 894-52-0
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C19-H16-O
- MOLECULAR WEIGHT :
- 260.35
- WISWESSER LINE NOTATION :
- L E5 B666 FVT&&&J C1 D1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 108 mg/kg/1Y-I
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 360 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Skin and Appendages - tumors
MUTATION DATA
- TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 50 ug/plate
- REFERENCE :
- CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 36,4525,1976
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相关化合物
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