N-hydroxy-N-glucuronosyl-2-aminofluorene
N-hydroxy-N-glucuronosyl-2-aminofluorene名称
[ CAS 号 ]:
89947-76-2
[ 英文名 ]:
N-hydroxy-N-glucuronosyl-2-aminofluorene
N-hydroxy-N-glucuronosyl-2-aminofluorene物理化学性质
[ 分子式 ]:
C19H19NO7
[ 分子量 ]:
373.35700
[ 精确质量 ]:
373.11600
[ PSA ]:
130.69000
[ LogP ]:
0.34560
N-hydroxy-N-glucuronosyl-2-aminofluorene毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- LZ6572570
- CHEMICAL NAME :
- beta-D-Glucopyranuronic acid, 1-deoxy-1-(9H-fluoren-2-ylhydroxyamino)-
- CAS REGISTRY NUMBER :
- 89947-76-2
- LAST UPDATED :
- 198910
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C19-H19-N-O7
- MOLECULAR WEIGHT :
- 373.39
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Parenteral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 5600 ug/kg/30W-C
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Kidney, Ureter, Bladder - tumors
MUTATION DATA
- TYPE OF TEST :
- Unscheduled DNA synthesis
- TEST SYSTEM :
- Human Cells - not otherwise specified
- DOSE/DURATION :
- 100 nmol/L
- REFERENCE :
- JJIND8 JNCI, Journal of the National Cancer Institute. (Washington, DC) V.61-79, 1978-87. For publisher information, see JNCIEQ. Volume(issue)/page/year: 72,847,1984
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