2-苯基苯酚
2-苯基苯酚用途
用于水果、蔬菜防腐保鲜
【用途二】
作防腐杀菌剂，我国规定可用于柑橘保鲜，最大使用量为3.0g/kg，残留量不大于12mg/kg。
【用途三】
作为防腐杀菌剂，我国规定还可用于柑橘保鲜，最大使用量为3.0g/kg，残留量不大于12mg/kg。
【用途四】
防霉剂；果蔬保鲜剂。主要用于柑橘类表皮的防霉。
欧洲经济共同体各国及美国除柑橘外，尚用于黄瓜、胡萝卜、苹果、甜瓜、番茄等。日本仅限用于柑橘类，最大残留量0.01g/kg(1990)。
各国的使用情况如下(允许用量，mg/kg)加拿大樱桃，5；柑橘类、黄瓜、胡椒、菠萝、番茄，10；甘薯，15；胡萝卜、桃、李属水果，20；苹果、梨，25；甜瓜，12。欧共体柑橘类，12。荷兰 柑橘类，10。英国柑橘类，70；苹果、梨、菠萝，10；甜瓜，125．美国(FDA，§180．129，2000)樱桃，5；柑橘类、黄瓜、葡萄、柚、金橘、柠檬、酸橙、橙、胡椒、菠萝、番茄、甘薯，15；胡萝卜、桃、李属，20；苹果、梨，25；罗马甜瓜，125(可食部分≤10)。
使用方法：将本品按约0.8%拌入蜡内，用喷洒或浸渍方式处理，能防止因白地霉(Gectricnumdidum)等引起的腐败。本品与联苯合用效果最佳。对于柑橘上由青霉(P．Digitation)引起的霉变，经3～5周，未处理品约60.5%发霉，而经本品处理后仅3.4%。
【用途五】
本品用于强力杀菌功能，用作木材、皮革、纸的防腐以及水果蔬菜肉类的储存防腐。
【用途六】
2-羟基联苯用作疏水性合成纤维氯纶、涤纶等采用载体染色法时的载体，表面活性剂，杀菌防腐剂，染料中间体。在日本，2-羟基联苯及基钠盐用于柑桔的防霉。在蜡中混入0.8%的本品，采用喷雾法在收获后的柑桔上，也可与联苯并用，可使腐兰降至最低限度。英、美、加拿大允许使用的水果范围较大，还包括苹果、梨、菠萝等。该品作为防腐剂还用于化妆品。2-羟基联苯对大鼠口服LD50为2.7-3.0g/kg。
【用途七】
荧光测定丙糖（trioses）的试剂。
2-苯基苯酚名称
[ CAS 号 ]:
90-43-7
[ 中文名 ]:
羟基联苯
[ 英文名 ]:
2-Phenylphenol
[中文别名 ]:
[英文别名 ]:
- O-PHENYLPHENOL
- ORTHO-PHENYLPHENOL,SODIUMSALT
- [1,1'-Biphenyl]-2-ol
- 2-HYDROXY DIPHENYL
- 2-HYDROXYBIPHENYL (2-PHENYLPHENOL)
- EINECS 201-993-5
- BIPHENYL-2-OL FOR SYNTHESIS
- ORTHO-PHENYLPHENOL(OPP)
- Orthoxenol
- OPP
2-苯基苯酚物理化学性质
[ 密度 ]:
1.1±0.1 g/cm3
[ 沸点 ]:
282.0±0.0 °C at 760 mmHg
[ 熔点 ]:
57-59 °C(lit.)
[ 分子式 ]:
C12H10O
[ 分子量 ]:
170.207
[ 闪点 ]:
123.9±0.0 °C
[ 精确质量 ]:
170.073166
[ PSA ]:
20.23000
[ LogP ]:
2.94
[ 外观性状 ]:
灰白色粉末
[ 蒸汽压 ]:
0.0±0.6 mmHg at 25°C
[ 折射率 ]:
1.605
[ 储存条件 ]:
库房通风低温干燥
[ 稳定性 ]:
Stable. Combustible. Incompatible with strong oxidizing agents, halogens.
[ 水溶解性 ]:
0.7 g/L (20 ºC)
2-苯基苯酚MSDS
2-苯基苯酚毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DV5775000
- CHEMICAL NAME :
- 2-Biphenylol
- CAS REGISTRY NUMBER :
- 90-43-7
- BEILSTEIN REFERENCE NO. :
- 0606907
- LAST UPDATED :
- 199806
- DATA ITEMS CITED :
- 43
- MOLECULAR FORMULA :
- C12-H10-O
- MOLECULAR WEIGHT :
- 170.22
- WISWESSER LINE NOTATION :
- QR BR
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2700 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1050 mg/kg
- TOXIC EFFECTS :
- Behavioral - ataxia Cardiac - other changes Lungs, Thorax, or Respiration - respiratory depression
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 50 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - cat
- DOSE/DURATION :
- 500 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - dyspnea Blood - hemorrhage
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 876 gm/kg/2Y-C
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - other changes Nutritional and Gross Metabolic - weight loss or decreased weight gain
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 728 gm/kg/2Y-C
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - changes in testicular weight
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 46500 mg/kg/31D-C
- TOXIC EFFECTS :
- Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 61250 ug/kg/7W-C
- TOXIC EFFECTS :
- Immunological Including Allergic - decrease in humoral immune response Immunological Including Allergic - decreased immune response
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2 gm/kg/2W-I
- TOXIC EFFECTS :
- Endocrine - changes in spleen weight Endocrine - changes in thymus weight Blood - changes in erythrocyte (RBC) count
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 31 gm/kg/31D-I
- TOXIC EFFECTS :
- Related to Chronic Data - death
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 478 gm/kg/91W-C
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 478 gm/kg/91W-C
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Kidney, Ureter, Bladder - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 135 gm/kg/26W-C
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria Kidney, Ureter, Bladder - tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 6 gm/kg
- SEX/DURATION :
- female 6-15 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Effects on Embryo or Fetus - fetal death
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 52168 mg/kg
- SEX/DURATION :
- male 13 week(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - testes, epididymis, sperm duct Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland, accessory glands
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 13050 mg/kg
- SEX/DURATION :
- female 7-15 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - Central Nervous System Reproductive - Specific Developmental Abnormalities - eye/ear Reproductive - Specific Developmental Abnormalities - musculoskeletal system
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 13050 mg/kg
- SEX/DURATION :
- female 7-15 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
- TYPE OF TEST :
- Unscheduled DNA synthesis
- TYPE OF TEST :
- DNA damage
MUTATION DATA
- TYPE OF TEST :
- Sister chromatid exchange
- TEST SYSTEM :
- Rodent - hamster Ovary
- DOSE/DURATION :
- 29900 ug/L
- REFERENCE :
- NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-301,1986 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 30,329,1983 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 30,329,1983 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81040 No. of Facilities: 7224 (estimated) No. of Industries: 67 No. of Occupations: 58 No. of Employees: 221003 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 81040 No. of Facilities: 15646 (estimated) No. of Industries: 135 No. of Occupations: 114 No. of Employees: 617394 (estimated) No. of Female Employees: 379044 (estimated)
2-苯基苯酚安全信息
[ 符号 ]:
GHS07, GHS09
[ 信号词 ]:
Warning
[ 危害声明 ]:
H315-H319-H335-H400
[ 警示性声明 ]:
P261-P273-P305 + P351 + P338
[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves
[ 危害码 (欧洲) ]:
Xi:Irritant
[ 风险声明 (欧洲) ]:
R36/37/38;R50
[ 安全声明 (欧洲) ]:
S22-S61
[ 危险品运输编码 ]:
UN 3077 9/PG 3
[ WGK德国 ]:
2
[ RTECS号 ]:
DV5775000
[ 包装等级 ]:
III
[ 危险类别 ]:
9
[ 海关编码 ]:
2907199011
2-苯基苯酚合成路线
2-苯基苯酚上下游产品
2-苯基苯酚上游产品
2-苯基苯酚下游产品
2-苯基苯酚制备
1、（1）环己烯基环己酮在三氧化二铝的存在下，进行脱氢反应而得；（2）将2-氨基联苯在硫酸中与亚硝酸钠反应，进行重氮化，生成联苯重氮盐，然后水解而得。
2、磺化法生产苯酚
3.（1）采用环己酮路线制备OPP，即以环己酮为原料，在酸催化下缩合脱水得到双聚中间体2-(1-环己烯基）环己酮和2-环己亚烷基环己酮，再经脱氢合成邻苯基苯酚。（2）从磺化法生产苯酚的副产物中得到邻苯基苯酚和对苯基苯酚的混合物，将其加热溶于三氯乙烯中，经冷却析出对位苯基苯酚结晶，经离心过滤，固体干燥得对苯基苯酚。母液用碳酸钠溶液洗涤后，加稀氢氧化钠中和，再酸化得邻苯基苯酚。
4. 从磺化法生产苯酚的副产物中得到邻苯基苯酚和对苯基苯酚的混合物,将其加热溶于三氯乙烯中,经冷却析出对位苯基苯酚结晶,经离心过滤,固体干燥得对苯基苯酚。母液用碳酸钠溶液洗涤后,加稀氢氧化钠中和,再酸化得邻苯基苯酚。
5. 烟草：FC，40。
2-苯基苯酚海关
[ 海关编码 ]: 2907199011
[ 中文概述 ]:
2907199011. 邻苯基苯酚及其盐. 增值税率:17.0%. 退税率:0.0%. 监管条件:S(进出口农药登记证明). 最惠国关税:5.5%. 普通关税:30.0%
[ 申报要素 ]: 品名, 成分含量, 用途
[ Summary ]:
2907199011. xylenols and their salts. VAT:17.0%. Tax rebate rate:0.0%. Supervision conditions:S(import or export registration certificate for pesticides). MFN tariff:5.5%. General tariff:30.0%
2-苯基苯酚文献
Talanta 146 , 694-706, (2015)
The aim of this study was to develop an analytical method and contribute to the assessment of the Exposome. Thus, a targeted analysis of a wide range of contaminants in contact with humans on daily ro...
A crystal structure of 2-hydroxybiphenyl 3-monooxygenase with bound substrate provides insights into the enzymatic mechanism.Biochim. Biophys. Acta 1854 , 1906-13, (2015)
2-Hydroxybiphenyl 3-monooxygenase (HbpA) is an FAD dependent monooxygenase which catalyzes the ortho-hydroxylation of a broad range of 2-substituted phenols in the presence of NADH and molecular oxyge...
Determination of phenolic disinfectants in consumer products by capillary electrophoresis with amperometric detection.J. Chromatogr. Sci. 48(7) , 584-8, (2010)
Numerous disinfection products are widely used in daily life to kill pathogenic microorganisms. However, most disinfectants are organic compounds that might be hazardous to the environment and humans ...
相关化工产品/化学物质：
推荐生产厂家/供应商：
公司名：上海化源世纪贸易有限公司
区域：上海市普陀区
价格：
联系人：徐经理
产品详情：2-苯基苯酚
公司名：上海吉至生化科技有限公司
区域：上海市奉贤区
价格：
￥138.0/500g
联系人：刘佳
产品详情：2-苯基苯酚
公司名：上海阿拉丁生化科技股份有限公司
区域：上海市浦东新区
价格：
￥298.0/250mg
￥需询单/1g
￥需询单/1g
￥需询单/1g
联系人：阿拉丁
产品详情：2-苯基苯酚
公司名：中山市迪欣化工有限公司
区域：中山市三角镇
价格：
￥65.0/200kg
联系人：陈雪萍
产品详情：邻苯基苯酚
公司名：西安康诺化工有限公司
区域：西安市雁塔区
价格：
￥需询单/1kg
联系人：高经理
产品详情：邻苯基苯酚
查看所有供应商请点击：
相关化合物
【2-苯基苯酚】化源网提供2-苯基苯酚CAS号90-43-7，2-苯基苯酚MSDS及其说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。CAS号查询2-苯基苯酚上化源网，专业又轻松。>>电脑版：2-苯基苯酚
标题：2-苯基苯酚_MSDS_用途_密度_2-苯基苯酚CAS号【90-43-7】_化源网 地址：https://m.chemsrc.com/mip/cas/90-43-7_832283.html