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BETA-葡萄糖醛酸甙酶

BETA-葡萄糖醛酸甙酶用途

β-葡萄糖醛酸酶是一种重要的溶酶体酶,参与含葡萄糖醛酸的糖胺聚糖的降解[1]。

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BETA-葡萄糖醛酸甙酶名称

[ CAS 号 ]:
9001-45-0

[ 中文名 ]:
beta-葡萄糖醛酸酶

[ 英文名 ]:
β-Glucuronidase from bovine liver

[中文别名 ]:

[英文别名 ]:

KETODASE
B-GLUCURONIDASE
EINECS 232-602-6
beta-glucuronideglucuronohydrolase
BETA-D-GLUCURONIDE GLUCURONOSOHYDROLASE TYPE B-10
BETA-D-GLUCURONIDE GLUCURONOSOHYDROLASE
BETA-D-GLUCURONIDE GLUCURONOSOHYDROLASE TYPE B-1
MFCD00130629

BETA-葡萄糖醛酸甙酶生物活性

[ 描述 ]:

β-葡萄糖醛酸酶是一种重要的溶酶体酶,参与含葡萄糖醛酸的糖胺聚糖的降解[1]。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

研究领域 >> 代谢疾病

[体外研究]

β-葡萄糖醛酸酶的缺乏导致粘多糖病VII型(MPSVII),导致溶酶体储存在大脑中[1]。

[参考文献]

[1]. Huma Naz, et al. Human β-glucuronidase: structure, function, and application in enzyme replacement therapy. Rejuvenation Res. 2013 Oct;16(5):352-63.

BETA-葡萄糖醛酸甙酶物理化学性质

[ 外观性状 ]:
固体

[ 储存条件 ]:
20°C

BETA-葡萄糖醛酸甙酶安全信息

[ 符号 ]:

GHS08

[ 信号词 ]:
Danger

[ 危害声明 ]:
H317-H334

[ 警示性声明 ]:
P261-P280-P342 + P311

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xn

[ 风险声明 (欧洲) ]:
42/43

[ 危险品运输编码 ]:
NONH for all modes of transport

[ RTECS号 ]:
LZ8990000

BETA-葡萄糖醛酸甙酶制备

以小牛肝为原料，匀浆后分别用硫酸铵和乙醇分级沉淀，再经过滤、等电聚焦、SephadexG-200层析得产品。

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BETA-葡萄糖醛酸甙酶文献

Relationship between the expression of CES2, UGT1A1, and GUSB in colorectal cancer tissues and aberrant methylation.

Neoplasma 61(1) , 99-109, (2014)

Irinotecan (CPT-11) is considered an important drug in the treatment of colorectal cancer, but its continuous administration reduces its sensitivity and influences the curative effect. The metabolism ...

Quantitative analysis of unconjugated and total bisphenol A in human urine using solid-phase extraction and UPLC-MS/MS: method implementation, method qualification and troubleshooting.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 1005 , 30-8, (2015)

The aim of the presented investigation was to document challenges encountered during implementation and qualification of a method for bisphenol A (BPA) analysis and to develop and discuss precautions ...

Identification of cortisol metabolites in the bile of Atlantic cod Gadus morhua L.

Steroids 88 , 26-35, (2014)

Interpretation of plasma cortisol levels in wild-caught fish is confounded by the stress of capture. Measurement of cortisol metabolites in fish bile could provide a method for assessing the stress le...

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