组织蛋白酶D 来源于牛脾脏

组织蛋白酶D 来源于牛脾脏用途

组织蛋白酶D是一种核内体-溶酶体天冬氨酸蛋白酶，与乳腺癌转移和阿尔茨海默病有关。人们发现，在凋亡的人包皮成纤维细胞中，溶酶体释放组织蛋白酶D先于释放细胞色素c和膜电位丧失。诱导凋亡后12至24小时，PC12细胞中的组织蛋白酶D水平升高。

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组织蛋白酶D 来源于牛脾脏名称

[ CAS 号 ]:
9025-26-7

[ 中文名 ]:
生化酶

[ 英文名 ]:
Cathepsin D, from bovine spleen

[英文别名 ]:

MFCD00130749

组织蛋白酶D 来源于牛脾脏生物活性

[ 描述 ]:

组织蛋白酶D(CTSD)是一种生物化学试剂,可作为生物材料或有机化合物用于生命科学相关研究。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

组织蛋白酶D 来源于牛脾脏物理化学性质

[ 密度 ]:
1.3±0.1 g/cm3

[ 沸点 ]:
432.4±45.0 °C at 760 mmHg

[ 分子式 ]:
C₁₅H₁₆O₃S

[ 分子量 ]:
276.351

[ 闪点 ]:
215.3±28.7 °C

[ 精确质量 ]:
276.082001

[ LogP ]:
3.16

[ 外观性状 ]:
冻干粉

[ 蒸汽压 ]:
0.0±1.1 mmHg at 25°C

[ 折射率 ]:
1.609

[ 储存条件 ]:
20°C

组织蛋白酶D 来源于牛脾脏安全信息

[ 危险品运输编码 ]:
NONH for all modes of transport

组织蛋白酶D 来源于牛脾脏文献

4-tert-Octylphenol stimulates the expression of cathepsins in human breast cancer cells and xenografted breast tumors of a mouse model via an estrogen receptor-mediated signaling pathway.

Toxicology 304 , 13-20, (2013)

Endocrine disrupting chemicals (EDCs) are defined as environmental compounds that modulate steroid hormone receptor-dependent responses an abnormal manner, resulting in adverse health problems for hum...

A periodate-cleavable linker for functional proteomics under slightly acidic conditions: application for the analysis of intracellular aspartic proteases.

J. Proteome Res. 12(1) , 199-207, (2013)

Specific elution of captured proteins greatly improves the quality of proteomic data obtained from pull-downs by avoiding signals from nonspecific proteins, thus allowing more sensitive identification...

Acetate-induced apoptosis in colorectal carcinoma cells involves lysosomal membrane permeabilization and cathepsin D release.

Cell Death Dis. 4 , e507, (2013)

Colorectal carcinoma (CRC) is one of the most common causes of cancer-related mortality. Short-chain fatty acids secreted by dietary propionibacteria from the intestine, such as acetate, induce apopto...

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