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5-羟基奥美拉唑

5-羟基奥美拉唑用途

5-Hydroxyomeprazole 是 Omeprazole (HY-B0113) 的主要代谢物。

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5-羟基奥美拉唑名称

[ CAS 号 ]:
92340-57-3

[ 中文名 ]:
5-羟基奥美拉唑

[ 英文名 ]:
5-hydroxy Omeprazole

[中文别名 ]:

[英文别名 ]:

Hydroxyomeprazole
5-Hydroxy Omeprazole Sodium Salt
HydroxyoMeprazole SodiuM Salt
5-hydroxymethylomeprazole

5-羟基奥美拉唑生物活性

[ 描述 ]:

5-Hydroxyomeprazole 是 Omeprazole (HY-B0113) 的主要代谢物。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

5-羟基奥美拉唑物理化学性质

[ 密度 ]:
1.45g/cm3

[ 沸点 ]:
656.3ºC at 760mmHg

[ 熔点 ]:
144-146ºC

[ 分子式 ]:
C₁₇H₁₉N₃O₄S

[ 分子量 ]:
361.41500

[ 闪点 ]:
350.7ºC

[ 精确质量 ]:
361.11000

[ PSA ]:
116.54000

[ LogP ]:
2.94930

[ 折射率 ]:
1.692

[ 储存条件 ]:
-20°C Freezer, Under Inert Atmosphere

5-羟基奥美拉唑MSDS

详细MSDS(安全技术说明书)

5-羟基奥美拉唑安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 危害码 (欧洲) ]:
Xi

[ 风险声明 (欧洲) ]:
36/37/38

[ 安全声明 (欧洲) ]:
26-36

[ 危险品运输编码 ]:
NONH for all modes of transport

5-羟基奥美拉唑文献

Development of an in vitro cytochrome P450 cocktail inhibition assay for assessing the inhibition risk of drugs of abuse.

Toxicol. Lett. 230(1) , 28-35, (2014)

Drugs of abuse are not tested for cytochrome P450 (CYP) inhibition potential before distribution. Therefore, a cocktail assay should be developed for testing the inhibition potential for all relevant ...

In vitro cytochrome P450 inhibition potential of methylenedioxy-derived designer drugs studied with a two-cocktail approach.

Arch. Toxicol. 90 , 305-18, (2016)

In vitro cytochrome P450 (CYP) inhibition assays are common approaches for testing the inhibition potential of drugs for predicting potential interactions. In contrast to marketed medicaments, drugs o...

Cytochrome P450 inhibition potential of new psychoactive substances of the tryptamine class.

Toxicol. Lett. 241 , 82-94, (2015)

New psychoactive substances (NPS) are not tested for their cytochrome P450 (CYP) inhibition potential before consumption. Therefore, this potential was explored for tryptamine-derived NPS (TDNPS) incl...

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