2-(4-氯-2-甲基苯氧基)丙酸
2-(4-氯-2-甲基苯氧基)丙酸用途
美托洛普是一种除草剂[1]。
点击显示
2-(4-氯-2-甲基苯氧基)丙酸名称
[ CAS 号 ]:
93-65-2
[ 中文名 ]:
2-(4-氯-2-甲基苯氧基)丙酸
[ 英文名 ]:
Mecoprop
[中文别名 ]:
[英文别名 ]:
- 2-MCPP
- EINECS 202-264-4
- Propanoic acid,2-(4-chloro-2-methylphenoxy)-
- 2-(4-Chloro-2-methylphenoxy)propanoic acid
- MFCD00002648
- UNII:74N8TKR9P8
- COMPITOX
- U 46
- 2M-4CP
- Clonotox
2-(4-氯-2-甲基苯氧基)丙酸生物活性
[ 描述 ]:
美托洛普是一种除草剂[1]。
[ 相关类别 ]:
[体外研究]
美托洛普(6.25和 62.5微米)可提高卵母细胞孵育培养基中睾酮 (62.5微米)和雌二醇 (6.25μM)浓度[1]
[参考文献]
2-(4-氯-2-甲基苯氧基)丙酸物理化学性质
[ 密度 ]:
1.3±0.1 g/cm3
[ 沸点 ]:
331.9±27.0 °C at 760 mmHg
[ 熔点 ]:
88-90ºC
[ 分子式 ]:
C10H11ClO3
[ 分子量 ]:
214.65
[ 闪点 ]:
154.5±23.7 °C
[ 精确质量 ]:
214.039673
[ PSA ]:
46.53000
[ LogP ]:
2.84
[ 外观性状 ]:
无色晶体
[ 蒸汽压 ]:
0.0±0.8 mmHg at 25°C
[ 折射率 ]:
1.542
[ 储存条件 ]:
APPROX 4°C
[ 水溶解性 ]:
水溶性：不溶；水溶解度：880 mg/l 25 °C；易溶于：二乙醚,丙酮,乙醇；可溶于：氯仿
2-(4-氯-2-甲基苯氧基)丙酸MSDS
2-(4-氯-2-甲基苯氧基)丙酸毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UE9750000
- CHEMICAL NAME :
- Propionic acid, 2-((4-chloro-o-tolyl)oxy)-
- CAS REGISTRY NUMBER :
- 93-65-2
- BEILSTEIN REFERENCE NO. :
- 2212752
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 23
- MOLECULAR FORMULA :
- C10-H11-Cl-O3
- MOLECULAR WEIGHT :
- 214.66
- WISWESSER LINE NOTATION :
- QVY1&OR DG B1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 650 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 402 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 369 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 650 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 900 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Bird - quail
- DOSE/DURATION :
- >500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 14400 mg/kg/90D-I
- TOXIC EFFECTS :
- Behavioral - food intake (animal) Blood - pigmented or nucleated red blood cells Nutritional and Gross Metabolic - weight loss or decreased weight gain
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 15 gm/kg/3W-I
- TOXIC EFFECTS :
- Skin and Appendages - dermatitis, other (after systemic exposure) Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 7 gm/kg
- SEX/DURATION :
- female 6-15 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Specific Developmental Abnormalities - musculoskeletal system
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 3 gm/kg
- SEX/DURATION :
- female 6-15 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 5 gm/kg
- SEX/DURATION :
- female 6-15 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue)
MUTATION DATA
- TEST SYSTEM :
- Rodent - mouse
- DOSE/DURATION :
- 100 mg/kg
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 55,197,1978 *** REVIEWS *** IARC Cancer Review:Human Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 41,357,1986 IARC Cancer Review:Group 2B IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,156,1987 TOXICOLOGY REVIEW DTTIAF Deutsche Tieraerztliche Wochenschrift. (Hanover, Fed. Rep. Ger.) V.1-77, 1893-1970. Volume(issue)/page/year: 80,485,1973 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M4007 No. of Facilities: 40 (estimated) No. of Industries: 2 No. of Occupations: 2 No. of Employees: 104 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M4007 No. of Facilities: 263 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 1578 (estimated)
点击显示
2-(4-氯-2-甲基苯氧基)丙酸安全信息
[ 危害码 (欧洲) ]:
Xn,N
[ 风险声明 (欧洲) ]:
R22;R38;R41;
[ 安全声明 (欧洲) ]:
S26;S37/S39
[ 危险类别 ]:
3.2
[ 海关编码 ]:
2918990022
2-(4-氯-2-甲基苯氧基)丙酸合成路线
2-(4-氯-2-甲基苯氧基)丙酸上下游产品
2-(4-氯-2-甲基苯氧基)丙酸上游产品
2-(4-氯-2-甲基苯氧基)丙酸下游产品
2-(4-氯-2-甲基苯氧基)丙酸海关
[ 海关编码 ]: 2918990022
[ 中文概述 ]:
2918990022. 2甲4氯、2甲4氯丙酸等〔包括精2甲4氯丙酸〕. 增值税率:17.0%. 退税率:9.0%. 监管条件:S(进出口农药登记证明). 最低关税:6.5%. 普通关税:30.0%
[ 申报要素 ]: 品名, 成分含量, 用途
[ 监管条件 ]: S.进出口农药登记证明
[ Summary ]:
2918990022 2-(4-chloro-2-methylphenoxy)acetic acid。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:30.0%
推荐生产厂家/供应商：
相关化合物
【2-(4-氯-2-甲基苯氧基)丙酸】化源网提供2-(4-氯-2-甲基苯氧基)丙酸CAS号93-65-2，2-(4-氯-2-甲基苯氧基)丙酸MSDS及其说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。CAS号查询2-(4-氯-2-甲基苯氧基)丙酸上化源网，专业又轻松。>>电脑版：2-(4-氯-2-甲基苯氧基)丙酸
标题：2-(4-氯-2-甲基苯氧基)丙酸_MSDS_用途_密度_CAS号【93-65-2】_化源网 地址：https://m.chemsrc.com/mip/cas/93-65-2_449374.html