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2,4-二甲基苯胺

2,4-二甲基苯胺用途

1.用作分析试剂，制造染料。
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2,4-二甲基苯胺名称

[ CAS 号 ]:
95-68-1

[ 中文名 ]:
2,4-二甲基苯胺

[ 英文名 ]:
2,4-Xylidine

[中文别名 ]:

[英文别名 ]:

2,4-二甲基苯胺物理化学性质

[ 密度 ]:
1.0±0.1 g/cm3

[ 沸点 ]:
214.7±9.0 °C at 760 mmHg

[ 熔点 ]:
16 °C

[ 分子式 ]:
C8H11N

[ 分子量 ]:
121.180

[ 闪点 ]:
90.6±0.0 °C

[ 精确质量 ]:
121.089149

[ PSA ]:
26.02000

[ LogP ]:
1.86

[ 外观性状 ]:
无色至黄色或暗棕色液体

[ 蒸汽密度 ]:
4.2 (vs air)

[ 蒸汽压 ]:
0.2±0.4 mmHg at 25°C

[ 折射率 ]:
1.559

[ 储存条件 ]:
库房通风低温干燥,与酸类、氧化剂、食品添加剂分开存放

[ 稳定性 ]:
Stable. Combustible. Incompatible with strong oxidizing agents, acids, acid anhydrides, acid chlorides, chloroformates, halogens.

[ 水溶解性 ]:
5 g/L (20 ºC)

2,4-二甲基苯胺MSDS

详细MSDS(安全技术说明书)

2,4-二甲基苯胺毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :
ZE8925000
CHEMICAL NAME :
2,4-Xylidine
CAS REGISTRY NUMBER :
95-68-1
BEILSTEIN REFERENCE NO. :
0636243
LAST UPDATED :
199806
DATA ITEMS CITED :
15
MOLECULAR FORMULA :
C8-H11-N
MOLECULAR WEIGHT :
121.20
WISWESSER LINE NOTATION :
ZR B1 D1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
467 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
149 ppm/7H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1170 mg/kg/10D-C
TOXIC EFFECTS :
Liver - changes in liver weight Kidney, Ureter, Bladder - changes in bladder weight Nutritional and Gross Metabolic - weight loss or decreased weight gain
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
13300 mg/kg/4W-I
TOXIC EFFECTS :
Liver - changes in liver weight Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - phosphatases Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other transferases
TYPE OF TEST :
DNA damage

MUTATION DATA

TEST SYSTEM :
Rodent - mouse
DOSE/DURATION :
200 mg/kg
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 46,305,1977 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 16,367,1978 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 16,367,1978 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987
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2,4-二甲基苯胺安全信息

[ 符号 ]:

GHS06, GHS08, GHS09

[ 信号词 ]:
Danger

[ 危害声明 ]:
H301 + H311 + H331-H373-H411

[ 警示性声明 ]:
Missing Phrase - N15.00950417-P260-P280-P302 + P352 + P312-P304 + P340 + P312-P403 + P233

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
T:Toxic;N:Dangerousfortheenvironment;

[ 风险声明 (欧洲) ]:
R23/24/25;R33;R51/53

[ 安全声明 (欧洲) ]:
S28-S36/37-S45-S61-S28A

[ 危险品运输编码 ]:
UN 1711 6.1/PG 2

[ WGK德国 ]:
2

[ RTECS号 ]:
ZE8925000

[ 包装等级 ]:
II

[ 危险类别 ]:
6.1

[ 海关编码 ]:
2921419000

2,4-二甲基苯胺合成路线

详细合成路线

2,4-二甲基苯胺上下游产品

2,4-二甲基苯胺上游产品

2,4-二甲基苯胺下游产品

2,4-二甲基苯胺制备

1.由间二甲基苯经硝化和还原而制得。
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2,4-二甲基苯胺海关

[ 海关编码 ]: 2921419000

[ 中文概述 ]:
HS:2921419000 苯胺盐 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2921419000 aniline and its salts。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

2,4-二甲基苯胺文献

cIEF for rapid pKa determination of small molecules: a proof of concept.

Eur. J. Pharm. Sci. 63 , 14-21, (2014)

A capillary isoelectric focusing (cIEF) method was developed for the determination of the ionization constants (pKa) of small molecules. Two approaches used to decrease the electroosmotic flow (EOF) w...

Stability of erythrocyte membrane and overall hemostasis potential - A biocompatibility study of mebrofenin and other iminodiacetic acid derivatives.

Pharmacol. Rep. 67 , 1230-9, (2015)

Intravenous injection seems to be the most convenient way of administering drugs and contrast agents, which makes components of the blood the first and usually unwanted target of their action. Binding...

Separation and analysis of dimethylaniline isomers by supercritical fluid chromatography—Electrospray ionization tandem mass spectrometry

J. Chromatogr. A. 1216(41) , 6970-3, (2009)

The assessment of human exposure to specific isomers of dimethylanilines (DMA's) is of interest for the evaluation of potential exposure-health outcome relationships. Improved analytical methods will ...


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公司名：上海吉至生化科技有限公司

区域：上海市奉贤区

价格：
￥238.0/500ml ￥68.0/100ml

联系人：刘佳

产品详情：2,4-二甲基苯胺

公司名：上海阿拉丁生化科技股份有限公司

区域：上海市浦东新区

价格：
￥360.0/500mg ￥需询单/1g ￥需询单/1g ￥需询单/1g

联系人：阿拉丁

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