2-丁酮肟
2-丁酮肟用途
用于有机合成
【用途二】
用于各种油基漆、醇酸漆、环氧酯漆等储运过程中的防结皮处理,也可用作硅固化剂
【用途三】
主要用于醇酸树脂涂料防结皮剂和硅固化剂。该品作为防止结皮的抗氧剂使用,比丁醛肟、环己酮肟的效果好。
【用途四】
涂料油漆油墨防结皮剂、异氰酸酯封闭剂、有机硅交联剂、有机合成中间体。
2-丁酮肟名称
[ CAS 号 ]:
96-29-7
[ 中文名 ]:
2-丁酮肟
[ 英文名 ]:
2-BUTANONE OXIME
[中文别名 ]:
[英文别名 ]:
- (2E)-N-Hydroxybutan-2-imine
- 2-BUTANONE OXIME
- 2-Butanone, oxime, (2E)-
- MFCD00013935
- EINECS 202-496-6
- (2E)-N-Hydroxy-2-butanimine
2-丁酮肟物理化学性质
[ 密度 ]:
0.9±0.1 g/cm3
[ 沸点 ]:
152.5±0.0 °C at 760 mmHg
[ 熔点 ]:
-30 °C
[ 分子式 ]:
C4H9NO
[ 分子量 ]:
87.120
[ 闪点 ]:
60.0±0.0 °C
[ 精确质量 ]:
87.068413
[ PSA ]:
32.59000
[ LogP ]:
0.65
[ 外观性状 ]:
透明液体
[ 蒸汽密度 ]:
3 (vs air)
[ 蒸汽压 ]:
1.9±0.5 mmHg at 25°C
[ 折射率 ]:
1.422
[ 储存条件 ]:
室温
[ 稳定性 ]:
Stable. Combustible. Incompatible with strong oxidizing agents. May react with strong acids to form an explosive material.
[ 水溶解性 ]:
114 g/L (20 ºC)
2-丁酮肟MSDS
2-丁酮肟毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- EL9275000
- CHEMICAL NAME :
- 2-Butanone, oxime
- CAS REGISTRY NUMBER :
- 96-29-7
- BEILSTEIN REFERENCE NO. :
- 1698241
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 24
- MOLECULAR FORMULA :
- C4-H9-N-O
- MOLECULAR WEIGHT :
- 87.14
- WISWESSER LINE NOTATION :
- QNUY2&1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 930 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LC - Lethal concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >50 gm/m3/4H
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2702 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 200 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 200 uL/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 6825 mg/kg/13W-I
- TOXIC EFFECTS :
- Endocrine - changes in spleen weight Blood - pigmented or nucleated red blood cells Blood - changes in erythrocyte (RBC) count
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 400 ppm/6H/4W-I
- TOXIC EFFECTS :
- Liver - changes in liver weight Endocrine - changes in spleen weight Blood - methemoglobinemia-carboxyhemoglobin
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1000 ppm/6H/8W-I
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Endocrine - changes in spleen weight Blood - methemoglobinemia-carboxyhemoglobin
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 14 mL/kg/4W-I
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - other changes Endocrine - changes in spleen weight Blood - changes in spleen
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 400 ppm/6H/4W-I
- TOXIC EFFECTS :
- Endocrine - changes in adrenal weight Endocrine - changes in spleen weight Blood - methemoglobinemia-carboxyhemoglobin
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1000 ppm/6H/8W-I
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Endocrine - changes in spleen weight Blood - methemoglobinemia-carboxyhemoglobin
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 75 ppm/6H/26W-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors
MUTATION DATA
- TYPE OF TEST :
- Mutation in mammalian somatic cells
- TEST SYSTEM :
- Rodent - mouse Lymphocyte
- DOSE/DURATION :
- 4600 mg/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 204,149,1988 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - T1326 No. of Facilities: 60 (estimated) No. of Industries: 1 No. of Occupations: 3 No. of Employees: 180 (estimated) NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 82905 No. of Facilities: 1540 (estimated) No. of Industries: 15 No. of Occupations: 36 No. of Employees: 12114 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 82905 No. of Facilities: 26030 (estimated) No. of Industries: 192 No. of Occupations: 112 No. of Employees: 313185 (estimated) No. of Female Employees: 25609 (estimated)
2-丁酮肟安全信息
[ 符号 ]:
GHS05, GHS07, GHS08
[ 信号词 ]:
Danger
[ 危害声明 ]:
H312-H317-H318-H351
[ 警示性声明 ]:
P280-P305 + P351 + P338
[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ 危害码 (欧洲) ]:
Xn:Harmful;
[ 风险声明 (欧洲) ]:
R21;R40;R41;R43
[ 安全声明 (欧洲) ]:
S13-S23-S26-S36/37/39-S61-S45-S36/37-S25
[ 危险品运输编码 ]:
UN 1993 3/PG 3
[ WGK德国 ]:
1
[ RTECS号 ]:
EL9275000
[ 包装等级 ]:
III
[ 危险类别 ]:
3
[ 海关编码 ]:
29280090
2-丁酮肟合成路线
2-丁酮肟上下游产品
2-丁酮肟上游产品
2-丁酮肟下游产品
2-丁酮肟制备
2-丁酮肟海关
[ 海关编码 ]: 2928000090
[ 中文概述 ]:
2928000090 其他肼(联氨)及胲(羟胺)的有机衍生物。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:6.5%。普通关税:20.0%
[ 申报要素 ]: 品名, 成分含量, 用途
[ Summary ]:
2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%
2-丁酮肟文献
Toxicol. Sci. 47(2) , 144-50, (1999)
Acetoxime and methylethyl ketoxime (MEKO) are tumorigenic in rodents, inducing liver tumors in male animals. The mechanisms of tumorigenicity for these compounds are not well defined. Oxidation of the...
Single-pot template transformations of cyanopyridines on a Pd(II) centre: syntheses of ketoimine and 2,4-dipyridyl-1,3,5-triazapentadiene palladium(II) complexes and their catalytic activity for microwave-assisted Suzuki-Miyaura and Heck reactions.Dalton Trans. (16) , 3074-84, (2009)
[2 + 3] cycloaddition of the pyrrolin N-oxide (-)O[upper bond 1 start](+)N[double bond, length as m-dash]CHCH(2)CH(2)C[upper bond 1 end]Me(2) with 2-cyanopyridine NC(5)H(4)(2-CN) in the presence of Pd...
Oxidative effects in human erythrocytes caused by some oximes and hydroxylamine.Arch. Toxicol. 72(5) , 270-6, (1998)
Both oximes and hydroxylamine (HYAM) are compounds with known oxidative capacity. We tested in vitro whether acetaldoxime (AAO), cyclohexanone oxime (CHO), methyl ethyl ketoxime (MEKO) or HYAM affect ...
相关化工产品/化学物质:
推荐生产厂家/供应商:
公司名:上海吉至生化科技有限公司
区域:上海市奉贤区
价格:
¥108.0/100ml
¥218.0/500ml
联系人:刘佳
产品详情:丁酮肟
公司名:上海阿拉丁生化科技股份有限公司
区域:上海市浦东新区
价格:
¥需询单/1mg
¥需询单/1mg
¥需询单/1mg
¥需询单/1mg
联系人:阿拉丁
产品详情:丁酮肟
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相关化合物
【2-丁酮肟】化源网提供2-丁酮肟CAS号96-29-7,2-丁酮肟MSDS及其说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。CAS号查询2-丁酮肟上化源网,专业又轻松。>>电脑版:2-丁酮肟
标题:2-丁酮肟_MSDS_用途_密度_2-丁酮肟CAS号【96-29-7】_化源网 地址:https://m.chemsrc.com/mip/cas/96-29-7_895865.html