美曲勃龙

美曲勃龙用途

An orally active anabolic-androgenic steroid and a 19-nortestosterone derivative that has been widely used in scientific research as a hot ligand in androgen receptor (AR) ligand binding assays (LBAs) and as a photoaffinity label for the AR..

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美曲勃龙名称

[ CAS 号 ]:
965-93-5

[ 中文名 ]:
美曲勃龙

[ 英文名 ]:
Methyltrienolone

[中文别名 ]:

[英文别名 ]:

17beta-hydroxy-17-methylestra-4,9,11-trien-3-one
17a-Methyl-3-oxo-4,9,11-estratrien-17b-ol
17α-Methyl-17β-hydroxyestra-4,9(10),11-trien-3-one
Methyltrienolone
(17b)-17-Hydroxy-17-methylestra-4,9,11-trien-3-one
17-β-Hydroxy-17-methylestra-4,9,11-trien-3-one
17α-Methyltrienolone
17α-Methyl-17β-hydroxyestra-4,9,11-trien-3-one
3-Oxo-17β-hydroxy-17α-methylestra-4,9,11-triene
17A-METHYL-TRENBOLONE

美曲勃龙物理化学性质

[ 密度 ]:
1.2±0.1 g/cm3

[ 沸点 ]:
485.9±45.0 °C at 760 mmHg

[ 熔点 ]:
206-209 °C

[ 分子式 ]:
C₁₉H₂₄O₂

[ 分子量 ]:
284.393

[ 闪点 ]:
206.3±21.3 °C

[ 精确质量 ]:
284.177643

[ PSA ]:
37.30000

[ LogP ]:
2.81

[ 蒸汽密度 ]:
5.31 (vs air)

[ 蒸汽压 ]:
0.0±2.8 mmHg at 25°C

[ 折射率 ]:
1.597

[ 储存条件 ]:
2-8°C

[ 水溶解性 ]:
INSOLUBLE

美曲勃龙安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H319

[ 警示性声明 ]:
P305 + P351 + P338

[ 危害码 (欧洲) ]:
F,Xi

[ 风险声明 (欧洲) ]:
R11:Highly Flammable. R43:May cause sensitization by skin contact.

[ 安全声明 (欧洲) ]:
S16-S36/37

[ 危险品运输编码 ]:
UN 1312 4.1/PG 3

[ WGK德国 ]:
2

[ RTECS号 ]:
DT5095000

[ 包装等级 ]:
III

[ 危险类别 ]:
4.1

[ 海关编码 ]:
29061900

美曲勃龙海关

[ 海关编码 ]: 29061900

美曲勃龙文献

Bisphenol A affects androgen receptor function via multiple mechanisms

Chem. Biol. Interact. 203(3) , 556-64, (2013)

• BPA antagonizes AR function by competitive inhibition of androgen binding. • Prevents functional foci formation in the nucleus. • Reduce the AR presence in the nucleus. • BPAF have similar activatio...

Hydrazinobenzoylcurcumin inhibits androgen receptor activity and growth of castration-resistant prostate cancer in mice.

Oncotarget 6(8) , 6136-50, (2015)

There is a critical need for therapeutic agents that can target the amino-terminal domain (NTD) of androgen receptor (AR) for the treatment of castration-resistant prostate cancer (CRPC). Calmodulin (...

The NLR-related protein NWD1 is associated with prostate cancer and modulates androgen receptor signaling.

Oncotarget 5(6) , 1666-82, (2014)

Prostate cancer (PCa) is among the leading causes of cancer-related death in men. Androgen receptor (AR) signaling plays a seminal role in prostate development and homeostasis, and dysregulation of th...

更多文献

美曲勃龙

美曲勃龙用途

美曲勃龙名称

美曲勃龙物理化学性质

美曲勃龙安全信息

美曲勃龙海关

美曲勃龙文献

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