对叔丁基苯酚
对叔丁基苯酚用途
用作合成抗氧剂
【用途二】
对叔丁基酚在农药上用于杀螨剂炔螨特的合成，也是杀菌剂新品种螺环菌胺(spiroxamine)的原料。它具有抗氧化性质，可用于橡胶、肥皂、氯代烃和硝化纤维的稳定剂；它是医药(驱虫剂)、香料、合成树脂的原料；软化剂、溶剂、染料与涂料的添加剂；还可用作油田用破乳剂成分及车用油添加剂。
【用途三】
（1）用于油溶性酚醛树脂，该品与甲醛缩聚可得到多种用途的产品。在氯丁系胶粘剂中掺入该品10-15%，获得可溶性树脂，此类胶粘剂主要用于运输，建筑、土木、制鞋等。在印刷油墨方面，可用于松香改性、胶版印刷、高级照相凹版等。在绝缘清漆方面，可应用于线圈浸渍清漆和层压板清漆等。（2）用于聚碳酸酯生产，作光气法聚碳酸酯的反应终止剂，添加量为树脂的1-3%。（3）用于环氧树脂、二甲苯树脂改性；作聚氯乙烯稳定剂、表面活性剂、紫外线吸收剂。（4）具有抗氧化性能，可用作橡胶、肥皂、氯代烃和硝化纤维的稳定剂。还是驱虫剂（医药）、杀螨剂克螨特（农药）及植物保护剂、香料、合成树脂的原料，也可用作软化剂、溶剂、染料与油漆的添加剂。还可用作油田用破乳剂的成分及车用机油添加剂。
【用途四】
本品用于聚碳酸树脂、叔丁基酚醛树脂、环氧树脂改性、二甲苯树脂改性、聚氯乙烯的稳定剂外，还用作紫外线吸收剂，农药、橡胶、涂料等防龟裂剂，润滑油的抗氧剂、分散剂、润滑剂、洗涤剂、助燃剂及苯乙烯的稳定剂、染料与油漆的添加剂及工业驱虫剂等。
对叔丁基苯酚名称
[ CAS 号 ]:
98-54-4
[ 中文名 ]:
4-叔丁基苯酚
[ 英文名 ]:
4-tert-Butylphenol
[中文别名 ]:
[英文别名 ]:
- 1-tert-Butyl-4-hydroxybenzene
- QR DX1&1&1
- 4-tert-Butylphenol
- Phenol, 4-(1,1-dimethylethyl)-
- MFCD00002367
- 4-(2-Methyl-2-propanyl)phenol
- p-tert-butylphenol
- EINECS 202-679-0
对叔丁基苯酚物理化学性质
[ 密度 ]:
1.0±0.1 g/cm3
[ 沸点 ]:
233.7±9.0 °C at 760 mmHg
[ 熔点 ]:
96-101 °C(lit.)
[ 分子式 ]:
C10H14O
[ 分子量 ]:
150.218
[ 闪点 ]:
110.9±8.2 °C
[ 精确质量 ]:
150.104462
[ PSA ]:
20.23000
[ LogP ]:
3.17
[ 外观性状 ]:
白色结晶粉末有一种消毒剂的气味
[ 蒸汽压 ]:
0.0±0.5 mmHg at 25°C
[ 折射率 ]:
1.514
[ 储存条件 ]:
库房通风低温干燥,与氧化剂分开存放
[ 稳定性 ]:
Stable. Incompatible with copper, steel, bases, acid chlorides, acid anhydrides, oxidizing agents.
[ 水溶解性 ]:
8.7 g/L (20 ºC)
对叔丁基苯酚MSDS
对叔丁基苯酚毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- SJ8925000
- CHEMICAL NAME :
- Phenol, p-(tert-butyl)-
- CAS REGISTRY NUMBER :
- 98-54-4
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 22
- MOLECULAR FORMULA :
- C10-H14-O
- MOLECULAR WEIGHT :
- 150.24
- WISWESSER LINE NOTATION :
- QR DX1&1&1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- DCTODJ Drug and Chemical Toxicology. (Marcel Dekker, 270 Madison Ave., New York, NY 10016) V.1- 1977/78- Volume(issue)/page/year: 11,43,1988
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,224,1986
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- DCTODJ Drug and Chemical Toxicology. (Marcel Dekker, 270 Madison Ave., New York, NY 10016) V.1- 1977/78- Volume(issue)/page/year: 11,43,1988
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,224,1986 ** ACUTE TOXICITY DATA **
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 3250 uL/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 30,470,1969
- TYPE OF TEST :
- LCLo - Lowest published lethal concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 5600 mg/m3/4H
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - respiratory depression Skin and Appendages - primary irritation (after topical exposure) Nutritional and Gross Metabolic - weight loss or decreased weight gain
- REFERENCE :
- DCTODJ Drug and Chemical Toxicology. (Marcel Dekker, 270 Madison Ave., New York, NY 10016) V.1- 1977/78- Volume(issue)/page/year: 11,43,1988
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 78 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 18,868,1975
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 2520 uL/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 30,470,1969
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - species unspecified
- DOSE/DURATION :
- 1500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 45(10),16,1980
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Mammal - species unspecified
- DOSE/DURATION :
- 1580 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 45(10),16,1980 ** TUMORIGENIC DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - hamster
- DOSE/DURATION :
- 252 gm/kg/20W-C
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria Gastrointestinal - tumors
- REFERENCE :
- CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 7,1285,1986 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 10 ppm (60 mg/m3);STEL 20 ppm (120 mg/m3) JAN 1993 OEL-AUSTRIA:TWA 0.08 ppm (0.5 mg/m3);Skin JAN 1993 OEL-DENMARK:TWA 0.08 ppm (0.5 mg/m3);Skin JAN 1993 OEL-GERMANY:TWA 0.08 ppm (0.5 mg/m3);Skin JAN 1993 OEL-SWITZERLAND:TWA 0.08 ppm (0.5 mg/m3);STEL 0.4 ppm;Skin JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81915 No. of Facilities: 3505 (estimated) No. of Industries: 42 No. of Occupations: 40 No. of Employees: 29500 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 81915 No. of Facilities: 4673 (estimated) No. of Industries: 55 No. of Occupations: 64 No. of Employees: 97601 (estimated) No. of Female Employees: 19779 (estimated)
对叔丁基苯酚安全信息
[ 符号 ]:
GHS05, GHS08, GHS09
[ 信号词 ]:
Danger
[ 危害声明 ]:
H315-H318-H361f-H411
[ 警示性声明 ]:
P201-P273-P280-P305 + P351 + P338 + P310-P308 + P313-P501
[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves
[ 危害码 (欧洲) ]:
Xi:Irritant;N:Dangerousfortheenvironment;
[ 风险声明 (欧洲) ]:
R37/38;R41;R51/53
[ 安全声明 (欧洲) ]:
S26-S39-S61
[ 危险品运输编码 ]:
UN 3077 9/PG 3
[ WGK德国 ]:
2
[ RTECS号 ]:
SJ8925000
[ 包装等级 ]:
III
[ 危险类别 ]:
8
[ 海关编码 ]:
2907199090
对叔丁基苯酚合成路线
对叔丁基苯酚上下游产品
对叔丁基苯酚上游产品
对叔丁基苯酚下游产品
对叔丁基苯酚制备
1.由苯酚与异丁烯为原料以阳离子交换树脂作催化剂制得。
2.由苯酚与二异丁烯反应制得。反应过程除得到叔丁基酚以外，还同时联产对辛基苯酚4-(tert-Octyl)phenol，[140-66-9]。
3.由苯酚与叔丁醇反应，经水洗、结晶、离心分离、干燥得成品。
4.对叔丁基酚有3种工艺路线。
(1)由苯酚与异丁烯为原料制得。
以阳离子交换树脂作催化剂，在流化床内于80～140℃进行催化烷基化，反应含量为60%～70%，所得混合叔丁基酚经固定床催化转位成对叔丁基酚，然后减压精馏，分离出过量苯酚再循环使用，并得产品对叔丁基酚，以异丁烯计收率为90%以上。
(2)由苯酸与2,4,4-三甲基-2-戊烯(二聚异丁烯)反应而得。
反应过程除得到对叔丁基酚以外，还同时联产对辛基苯酚。
(3)由苯酚与叔丁醇反应而得。
将无水三氯化铝与石油醚混合，搅拌下慢慢加入苯酚，用冰水冷却，再慢慢加入叔丁醇，加完后搅拌15min，再分批加入无水三氯化铝，最后搅拌4～5h，慢慢加到1∶1盐酸中，静置，分出石油层，水层用石油醚提取，合并石油醚溶液用水洗涤，分净水后回收石油醚，减压蒸馏得成品。采用此工艺进行工业生产时，合成反应在145～150℃下进行。
采用杂多酸催化合成 将苯酚、杂多酸催化剂H4SiW12O40·狓H2O一起加入反应器中，在不断搅拌下加热到110℃，匀速通入一定量的异丁烯气体，反应4～5h，倒出反应液进行水洗、重结晶、过滤、干燥即得成品。较佳的反应条件是：反应温度110℃，苯酚与异丁烯的摩尔比为1∶2，反应时间为4.5h，催化剂用量占苯酚质量的３％，在该条件下，产品的收率可达85%，与硫酸催化合成对叔丁基苯酚相比，提高收率20%左右。
对叔丁基苯酚海关
[ 海关编码 ]: 2907199090
[ 中文概述 ]:
2907199090 其他一元酚. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:5.5% 普通关税:30.0%
[ 申报要素 ]: 品名, 成分含量, 用途
[ Summary ]:
2907199090 other monophenols VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%
对叔丁基苯酚文献
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标题：对叔丁基苯酚_MSDS_用途_密度_对叔丁基苯酚CAS号【98-54-4】_化源网 地址：https://m.chemsrc.com/mip/cas/98-54-4_120.html