碘苯酯

碘苯酯用途

碘苯酯(泛不透明)是一种高度亲脂性物质,可用作造影剂。碘苯酯主要用于脑和脊髓可视化[1][2]。

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碘苯酯名称

[ CAS 号 ]:
99-79-6

[ 中文名 ]:
碘苯酯

[ 英文名 ]:
iofendylate

[英文别名 ]:

Iophendylate,p
10-(4-Jod-phenyl)-undecansaeure-aethylester
Aethyl-9-(p-Iodphenyl)-9-methyl-decanoat
Ethiodan
Iofendylate
Mulsopaque
Neurotrast
IOPHENDYLATE
10-(4-iodo-phenyl)-undecanoic acid ethyl ester
Jofendylatum

碘苯酯生物活性

[ 描述 ]:

碘苯酯(泛不透明)是一种高度亲脂性物质,可用作造影剂。碘苯酯主要用于脑和脊髓可视化[1][2]。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

碘苯酯物理化学性质

[ 密度 ]:
1.261g/cm3

[ 沸点 ]:
421.2ºC at 760mmHg

[ 熔点 ]:
25°C

[ 分子式 ]:
C₁₉H₂₉IO₂

[ 分子量 ]:
416.33700

[ 闪点 ]:
208.5ºC

[ 精确质量 ]:
416.12100

[ PSA ]:
26.30000

[ LogP ]:
6.07860

[ 折射率 ]:
1.526

碘苯酯毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: YQ2550000

CHEMICAL NAME :: Undecanoic acid, 10-(p-iodophenyl)-, ethyl ester

CAS REGISTRY NUMBER :: 99-79-6

BEILSTEIN REFERENCE NO. :: 2661373

LAST UPDATED :: 199612

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C19-H29-I-O2

MOLECULAR WEIGHT :: 416.38

WISWESSER LINE NOTATION :: IR DY1&8VO2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,65,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1130 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 34,38,1971

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 5640 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 34,38,1971

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: RADLAX Radiology. (Radiological Soc. of North America, 20th & Northampton Sts., Easton, PA 18042) V.1- 1923- Volume(issue)/page/year: 43,230,1944

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 34,38,1971 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4722 No. of Facilities: 16 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 702 (estimated) No. of Female Employees: 359 (estimated)

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碘苯酯安全信息

[ 海关编码 ]:
2916399090

碘苯酯合成路线

详细合成路线

碘苯酯上下游产品

碘苯酯上游产品

碘苯酯下游产品

碘苯酯海关

[ 海关编码 ]: 2916399090

[ 中文概述 ]:
2916399090 其他芳香一元羧酸. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 丙烯酸、丙烯酸盐或酯应报明包装

[ Summary ]:
2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

碘苯酯