CYS-TYR-CYS-ARG-ILE-PRO-ALA-CYS-ILE-ALA-GLY-GLU-ARG-ARG-TYR-GLY-THR-CYS-ILE-TYR-GLN-GLY-ARG-LEU-TRP-ALA-PHE-CYS-CYS (DISULFIDE BRIDGE: CYS1-CYS29,CYS3-CYS18,CYS8-CYS28)

用途

防御素HNP-2是人类中性粒细胞产生的内源性抗生素肽和单核细胞趋化肽。

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名称

[ 中文名 ]:
CYS-TYR-CYS-ARG-ILE-PRO-ALA-CYS-ILE-ALA-GLY-GLU-ARG-ARG-TYR-GLY-THR-CYS-ILE-TYR-GLN-GLY-ARG-LEU-TRP-ALA-PHE-CYS-CYS (DISULFIDE BRIDGE: CYS1-CYS29,CYS3-CYS18,CYS8-CYS28)

[ 英文名 ]:
Defensin HNP-2 human

[英文别名 ]:

Defensin HNP-2 human
HNP2
HNP-2, Defensin Human Neutrophil Peptide-2

生物活性

[ 描述 ]:

防御素HNP-2是人类中性粒细胞产生的内源性抗生素肽和单核细胞趋化肽。

[ 靶点 ]

Human Endogenous Metabolite

物理化学性质

[ 分子式 ]:
C₁₄₇H₂₁₇N₄₃O₃₇S₆

[ 分子量 ]:
3370.95000

[ 精确质量 ]:
3368.47000

[ PSA ]:
1445.83000

[ LogP ]:
6.15780

MSDS

详细MSDS(安全技术说明书)

安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

文献

Structure, function, and membrane integration of defensins.

Curr. Opin. Struct. Biol. 5 , 521-527, (1995)

Defensins comprise a structural class of small cationic peptides that exert broad-spectrum antimicrobial activities through membrane permeabilization. Their predominantly beta-sheet structure, stabili...

Purification, primary structure, and antimicrobial activities of a guinea pig neutrophil defensin.

Infect. Immun. 55 , 2281, (1987)

A broad-spectrum antimicrobial peptide present in guinea pig neutrophils was isolated, characterized biochemically, and assessed for microbicidal range and potency in vitro. The guinea pig neutrophil ...

Human β-defensin-2. Schroder J.M., and Harder, J.

Int. J. Biochem. Cell Biol. 31 , 645-651, (1998)

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