阿维A酸

产品详情：

更新时间： 2024-09-28 17:17:26

CAS号：55079-83-9

常用名： 阿维A酸

价格：
￥需询单/1kg

纯度： 99.0%

备货期： 3天

库存： 询单

其他详情（用途，包装）：
用途： Acitretin(Ro 10-1670) is a second-generation, systemic retinoid that has been used in the treatment of psoriasis.Target: RAR/RXRAcitretin is a second-generation, systemic retinoid that has been approved for the treatment of psoriasis since 1997. It can be considered one of the treatments of choice for pustular and erythrodermic psoriasis. However, the efficacy of acitretin as a monotherapy for plaque psoriasis is less, although it is often used in combination therapy with other systemic psoriasis therapies, especially ultraviolet B or psoralen plus ultraviolet A phototherapy, to increase efficacy. Such combination treatments may potentially minimise toxicity by using lower doses of each of the two agent [1].Thirty-nine male adult Wistar albino rats were divided into 3 groups as two experimental groups and one control group. The first group consisting 14 rats were applied orally standard dose (0.75 mg/kg/day) acitretin and the second group consisting 16 rats were applied high dose (1.5 mg/kg/day) acitretin.Acitretin was given within dimetil sulphoxide (DMSO), which was diluted with saline solution as a ratio of 1/10, in order to increase its solubility. The control group consisting 9 rats were given only saline solution including DMSO for 8 weeks. After 8 weeks of the administration, half of the rats in the first and second groups and the entire control group were sacrificed under deep ether anaesthesia and bilateral orchiectomy was made. The remainingrats were compared with the control group using a similar method at the end of 8 weeks of wash-off period. The orchiectomy materials were histopathologically evaluated under the light microscope for spermatogenesis according to parameters including spermatogenetic activity, spermatogenetic organization, seminiferous tubular diameter, interstitial Leydig cells and fibroblasts. In our study it was concluded that the standard and high doses of acitretin do not have any effect on the spermatogenesis of threats [2].Clinical indications: PsoriasisFDA Approved Date: Toxicity: nausea; headache; itching; red or flaky skin; dry or red eyes; dry mouth; depression; 0cystitis acne or hair loss 物理化学性质： CAS号：55079-83-9 常用中文名：阿维A酸常用英文名：Acitretin 分子式：C21H26O3 分子量：326.429 密度：1.1±0.1 g/cm3 沸点：521.3±38.0 °C at 760 mmHg 熔点：228-230ºC 闪点：180.3±20.3 °C 储存条件：2-8°C

供应商信息：

公司名：杭州德立化工有限公司

认证状态： 未认证供应商

商品数： 10件

电话： +86-13819157606

地址： 古墩路387号金桂大厦1115室

地区： 杭州市西湖区

联系人： 朱赛峰

联系人电话： +8613819157606

邮件：1585639177@qq.com

网址：http://www.dlchemical.com/

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公司介绍：
杭州德立化工有限公司成立于2001年，是一家专业生产医药原料药、医药中间体和其他化工品的工厂。我公司生产基地分别位于湖州，杭州余杭和建德。位于杭州余杭塘栖工业园区的老厂占地面积约100多亩，新厂按照GMP要求建设并已经投入生产，公司拥有一批素质良好的员工队伍，其中高、中级科技人员达50多名。公司拥有健全的生产设备、先进的生产工艺、齐全的检测设施，能独立完成产品的开发、设计和生产过程，并和浙江大学合作开发更先进的技术和定制产品，同时在杭州市区设有销售和R&D中心。
我公司生产的产品主要有屈螺酮、阿维A酸、异维A酸、盐酸氨溴索、盐酸溴己新、地奥司明、酒石酸溴莫尼定、盐酸依匹斯汀等原料药及中间体，产品工艺成熟，质量稳定，并符合多个药典版本，产品主要出口欧洲、印度、南美及东南亚市场。
公司秉承以“质量为主、信誉为本”的经营宗旨，以优质的产品，专业的服务与您真诚合作，互惠共赢，我们愿意和各位同仁一起，再接再厉，开创更美好的明天。

其他供应商价格：

2022-02-19 价格：￥74.9 阿曲汀

2021-02-06 价格：￥1489.0 Acitretin

2024-05-13 价格：￥需询单 N, N'-二羟乙基哌嗪

2023-10-13 价格：￥需询单阿维A酸 Acitretin

2017-08-07 价格：￥需询单阿维A

2024-01-09 价格：$需询单 Acitretin

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阿维A酸价格

阿维A酸

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