牛蒡苷

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更新时间： 2026-06-29 16:35:55

CAS号：20362-31-6

常用名： 牛蒡子苷

价格：
￥需询单/1kg ￥需询单/100g ￥需询单/100kg ￥需询单/1ton

纯度： 98.0%

备货期： 需询单

库存： 询单

其他详情（用途，包装）：
用途： Arctiin(NSC 315527), a plant lignan that can be extracted from the Arctium lappa (burdock) seeds, is a possible environmental endocrine disruptor compounds and have been shown to influence sex hormone metabolism as well as protein synthesis, steroid biosynthesis. IC50 Value:Target: Othersin vitro: Treatment of PC-3 cells with arctiin decreased the cell number in a concentration- and time-dependent manner in serum-containing condition. Arctiin preferentially induced cell detachment, but did not have anti-proliferation or cytotoxic effects in PC-3 cells. The arctiin-induced effect was inhibited by cycloheximide, indicating that protein synthesis was required [1]. Although arctiin, the active component of AL that has been described in the literature, was not able to reduce degranulation in RBL-2H3 cells, a single high-performance liquid chromatography (HPLC) fraction from the AL extract inhibited beta-hexosaminidase release (IC(50) = 22.2 microg/ml) [2]. The growth inhibition caused by arctiin is associated with the down-regulation of cyclin D1 protein expression. Furthermore, thearctiin-induced suppression of cyclin D1 protein expression occurs in various types of human tumor cells, including osteosarcoma, lung, colorectal, cervical and breast cancer, melanoma, transformed renal cells and prostate cancer. Depletion of the cyclin D1 protein using small interfering RNA-rendered human breast cancer MCF-7 cells insensitive to the growth inhibitory effects of arctiin, implicates cyclin D1 as an important target of arctiin [6]. in vivo: Histopathological evaluation of prostate revealed that all the rats in any group developed adenocarcinoma in dorsolateral lobe of prostate, except two rats in 0.1% arctiin treated and one rat in 0.002% arctiin treated groups without prostate adenocarcinoma development [3]. After oral administration of arctiin (30, 60, 120 mg/kgd) for three weeks, the levels of serum creatinine (Scr) and blood urea nitrogen (BUN) and 24-h urine protein content markedly decreased, while endogenous creatinine clearance rate (ECcr) significantly increased [4]. STZ-induced diabetic rats were treated witharctiin at the dosage of 60 or 40 mg/kg/day via intraperitoneal injection for 8 weeks. Blood glucose and 24-h urinary albumin content were measured, and kidney histopathological changes were monitored [5]. 物理化学性质： CAS号：20362-31-6 常用中文名：牛蒡子苷常用英文名：Arctiin 分子式：C27H34O11 分子量：534.552 密度：1.4±0.1 g/cm3 沸点：756.4±60.0 °C at 760 mmHg 熔点：109 °C 闪点：250.1±26.4 °C 储存条件：?20°C

供应商信息：

公司名：上海亚兴生物医药科技有限公司

认证状态： 未认证供应商

商品数： 1621件

电话： +8621-58956006

地址： 妙镜路1111号

地区： 上海市浦东新区

联系人： 段博

联系人电话： +86-21-58956006

邮件：sales4@langchem.com

网址：http://isotopemall.com/

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公司介绍：
上海亚兴生物医药科技有限公司于2014年5月成立，是一家专业从事生物医药的研发、生产和销售的企业。公司目前有两个生产基地，分别在江苏南通市和江苏徐州市。上海拥有3000平方的研发中心，公司目前拥有研发生产团队100余人，博士5人。主要以工业自动化为研究对象，生产高纯度、高产量、高稳定性的产品。公司具备先进检测设备，包括HPLC,GC,TLC,MS 等。目前生产基地都是以先进的流体自动化反应设备为主，包括流动相氢化，酯化，溴化，脱水等自动化生产设备。公司致力于先进自动化设备研发，替代传统反应器。以技术为驱动力，以客户需求为导向，为客户提供更快捷高效的服务，通过不断的生产实践，实现生物医药绿色工艺，为社会创造价值。
上海亚兴生物为客户提供各类氘代化合物的定制服务，产品包括氘代医药中间体，氘代OLED材料等。同时也承接各类医药企业产品生产，工艺开发等。

其他供应商价格：

2024-09-29 价格：￥需询单牛蒡子苷

2022-02-19 价格：￥247.9 牛蒡子苷

2025-09-17 价格：￥需询单牛蒡苷

2025-12-29 价格：￥需询单牛蒡子苷

2019-03-05 价格：￥118.0 牛蒡子苷/牛蒡苷

2024-09-13 价格：￥需询单牛蒡苷，牛蒡子苷

2025-01-03 价格：￥需询单牛蒡苷

2024-07-15 价格：需询单牛蒡子苷

2018-03-25 价格：￥需询单牛蒡子苷

2018-07-13 价格：￥180.0 牛蒡子苷

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牛蒡子苷价格

牛蒡苷

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