Entecavir
产品详情：
更新时间： 2021-04-01 19:25:19
CAS号：142217-69-4
常用名：
价格：
$需询单/1kg
纯度： 99.9%
备货期： 需询单
库存： 现货
其他详情（用途，包装）：
Names
[ Name ]: entecavir (anhydrous)
[ Synonym ]: More Synonyms
Chemical & Physical Properties
[ Density ]: 1.8±0.1 g/cm3
[ Boiling Point ]: 734.2ºC at 760 mmHg
[ Melting Point ]: 249-252ºC
[ Molecular Formula ]: C12H15N5O3
[ Molecular Weight ]: 277.279
[ Flash Point ]: 397.9ºC
[ Exact Mass ]: 277.117493
[ PSA ]: 130.05000
[ LogP ]: -0.96
[ Index of Refraction ]: 1.837
MSDS
Material Safety Data Sheet
Section1. Identification of the substance
Product Name: Entecavir
Synonyms:
Section2. Hazards identification
Harmful by inhalation, in contact with skin, and if swallowed.
Section3. Composition/information on ingredients.
Ingredient name:Entecavir
CAS number:142217-69-4
Section4. First aid measures
Skin contact:Immediately wash skin with copious amounts of water for at least 15 minutes while removing
contaminated clothing and shoes. If irritation persists, seek medical attention.
Eye contact:Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate
flushing of the eyes by separating the eyelids with fingers. If irritation persists, seek medical
attention.
Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention.
Ingestion:Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention.
Section5. Fire fighting measures
In the event of a fire involving this material, alone or in combination with other materials, use dry
powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus
should be worn.
Section6. Accidental release measures
Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national
standards.
Respiratory precaution:Wear approved mask/respirator
Hand precaution:Wear suitable gloves/gauntlets
Skin protection:Wear suitable protective clothing
Eye protection:Wear suitable eye protection
Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container
for disposal. See section 12.
Environmental precautions: Do not allow material to enter drains or water courses.
Section7. Handling and storage
Handling:This product should be handled only by, or under the close supervision of, those properly qualified
in the handling and use of potentially hazardous chemicals, who should take into account the fire,
health and chemical hazard data given on this sheet.
Storage:Store in closed vessels, refrigerated.
Section8. Exposure Controls / Personal protection
Engineering Controls: Use only in a chemical fume hood.
Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles.
General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse.
Section9. Physical and chemical properties
Appearance:Not specified
Boiling point:No data
Melting point:No data
Flash point:No data
Density:No data
Molecular formula: C12H15N5O3
Molecular weight: 277.3
Section10. Stability and reactivity
Conditions to avoid: Heat, flames and sparks.
Materials to avoid: Oxidizing agents.
Possible hazardous combustion products: Carbon monoxide, nitrogen oxides.
Section11. Toxicological information
No data.
Section12. Ecological information
No data.
Section13. Disposal consideration
Arrange disposal as special waste, by licensed disposal company, in consultation with local waste
disposal authority, in accordance with national and regional regulations.
Section14. Transportation information
Non-harzardous for air and ground transportation.
Section15. Regulatory information
No chemicals in this material are subject to the reporting requirements of SARA Title III, Section
302, or have known CAS numbers that exceed the threshold reporting levels established by SARA
Title III, Section 313.
SECTION 16 - ADDITIONAL INFORMATION
N/A
Safety Information
[ RIDADR ]: NONH for all modes of transport
[ HS Code ]: 2933990090
Synthetic RoutePrevious 1/19 Next
6-chloroentecavir
701278-58-2
6-chloroentecav...
~71%
Entecavir
142217-69-4
Entecavir
Literature: HANMI HOLDINGS CO., LTD. Patent: US2011/251387 A1, 2011 ; Location in patent: Page/Page column 8 ;
tert-butyl (6-iodo-9-((4aR,6S,7aS)-2-methyl-5-methylenehexahydrocyclopenta[d][1,3]dioxin-6-yl)-9H-purin-2-yl)carbamate
1328921-77-2
tert-butyl (6-i...
~88%
Entecavir
142217-69-4
Entecavir
Literature: ScinoPharm Taiwan, Ltd. Patent: US2011/201809 A1, 2011 ; Location in patent: Page/Page column 18 ;
6-(benzyloxy)-9-((4aR,6S,7aS)-5-methylene-2-phenylhexahydrocyclopenta[d][1,3]dioxin-6-yl)-N-(trimethylsilyl)-9H-purin-2-amine
1351691-93-4
6-(benzyloxy)-9...
~86%
Entecavir
142217-69-4
Entecavir
Literature: ALPHORA RESEARCH INC.; ALBERICO, Dino; CLAYTON, Joshua; DIXON, Craig; GORIN, Boris Patent: WO2011/150512 A1, 2011 ; Location in patent: Page/Page column 11 ;
Precursor & DownStream
Precursor 4
6-chloroentecavir Structure CAS#:701278-58-2
6-chloroentecavir
6-(benzyloxy)-9-((4aR,6S,7aS)-5-methylene-2-phenylhexahydrocyclopenta[d][1,3]dioxin-6-yl)-N-(trimethylsilyl)-9H-purin-2-amine Structure CAS#:1351691-93-4
6-(benzyloxy)-9...
9-[(1S,3R,4S)-4-tert-butyldimethylsilyloxy-3-(tert-butyldimethylsilyloxymethyl)-2-methylene-cyclopentyl]-6-chloro-9H-purine-2-carbamic acid tert-butyl ester Structure CAS#:1354715-15-3
9-[(1S,3R,4S)-4...
6-chloro-9-[(1S,3R,4S)-4-hydroxy-3-hydroxymethyl-2-methylene-cyclopentyl]-N-(tert-butyloxycarbonyl)-9H-purine-2-carbamic acid tert-butyl ester Structure CAS#:1354715-31-3
6-chloro-9-[(1S...
DownStream 0
Customs
[ HS Code ]: 2933990090
[ Summary ]: 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
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Decreased liver distribution of entecavir is related to down-regulation of Oat2/Oct1 and up-regulation of Mrp1/2/3/5 in rat liver fibrosis.
Eur. J. Pharm. Sci. 71 , 73-9, (2015)
We aimed to elucidate whether entecavir was taken-up into liver by transporters and clarify the possible molecular mechanisms of changes in the distribution of entecavir in rat liver fibrosis.Thioacet...
Detail
Synonyms
2-Amino-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-1,9-dihydro-6H-purin-6-one
entecavir (anhydrous)
6H-Purin-6-one, 2-amino-1,9-dihydro-9-((1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl)-
2-amino-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-3H-purin-6-one
2-amino-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-1,9-dihydro-6H-purin-6-one
6H-Purin-6-one, 2-amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-
Baraclude
entecavir
9H-purin-6-ol, 2-amino-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-
UNII-NNU2O4609D
2-amino-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-9H-purin-6-ol
供应商信息：
公司名：济南德普顿斯化工科技有限公司
认证状态： 未认证供应商
商品数： 160件
电话： 0532-80919617
地址： 济南市高新区舜华路750号A408室
地区： 济南市市中区
联系人： 秦秀坤
联系人电话： 18153243071
邮件：bdlzhipin@aliyun.com
网址：http://
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公司介绍：
推荐生产厂家/供应商：
公司名：上海源溪生物科技有限公司
区域：上海市浦东新区
价格：
￥需询单/1g
联系人：赖经理
产品详情：
公司名：上海阿摩尔生物科技有限公司
区域：上海市奉贤区
价格：
￥需询单/100mg
￥需询单/1g
￥需询单/250mg
￥需询单/5g
联系人：王汐瑶
产品详情：
公司名：上海阿拉丁生化科技股份有限公司
区域：上海市浦东新区
价格：
￥389.9/250mg
￥955.9/1ml
￥778.9/1g
￥288.9/50mg
联系人：阿拉丁
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2018-05-03 价格：￥需询单
2019-05-20 价格：￥180000.0
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Entecavir价格为$需询单/1kg, 由Entecavir生产厂家济南德普顿斯化工科技有限公司提供，供应信息包括纯度，备货期/库存，供货能力等。>>电脑版：Entecavir_价格_生产厂家【济南德普顿斯化工科技有限公司】
标题：Entecavir - 生产厂家：济南德普顿斯化工科技有限公司 地址：https://m.chemsrc.com/mip/chanpin/3974155.html