Adefovir

产品详情：

更新时间： 2024-09-23 15:24:58

CAS号：106941-25-7

常用名： 阿德福韦

价格：
$需询单/1kg

纯度： 99.9%

备货期： 需询单

库存： 现货

其他详情（用途，包装）：
Names
[ Name ]: Adefovir
[ Synonym ]: More Synonyms
Chemical & Physical Properties
[ Density ]: 1.9±0.1 g/cm3
[ Boiling Point ]: 632.5±65.0 °C at 760 mmHg
[ Melting Point ]: >260°C
[ Molecular Formula ]: C8H12N5O4P
[ Molecular Weight ]: 273.186
[ Flash Point ]: 336.3±34.3 °C
[ Exact Mass ]: 273.062683
[ PSA ]: 146.19000
[ LogP ]: -2.06
[ Vapour Pressure ]: 0.0±2.0 mmHg at 25°C
[ Index of Refraction ]: 1.769
MSDS
Adefovir MSDS(Chinese)
Toxicological Information
CHEMICAL IDENTIFICATION
RTECS NUMBER :
SZ6563500
CHEMICAL NAME :
Phosphonic acid, ((2-(6-amino-9H-purin-9-yl)ethoxy)methyl)-
CAS REGISTRY NUMBER :
106941-25-7
LAST UPDATED :
199712
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C8-H12-N5-O4-P
MOLECULAR WEIGHT :
273.22
HEALTH HAZARD DATA
ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
MUTATION DATA

TEST SYSTEM :
Insect - Drosophila melanogaster
DOSE/DURATION :
100 ppm
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 311,305,1994
Safety Information
[ Symbol ]: GHS06
GHS06
[ Signal Word ]: Danger
[ Hazard Statements ]: H301
[ Precautionary Statements ]: P301 + P310
[ Hazard Codes ]: Xi
[ Risk Phrases ]: R36/37/38:Irritating to eyes, respiratory system and skin .
[ Safety Phrases ]: S26
[ RIDADR ]: UN 2585 8/PG 3
[ WGK Germany ]: 2
[ RTECS ]: SZ6563500
[ Packaging Group ]: III
[ Hazard Class ]: 8
[ HS Code ]: 2933990090
Synthetic RoutePrevious 1/4 Next
Diethyl ((2-(6-amino-9H-purin-9-yl)ethoxy)methyl)phosphonate
116384-53-3

Diethyl ((2-(6-...

~95%

Adefovir
106941-25-7

Adefovir

Literature: Nucleosides and Nucleotides, , vol. 17, # 8 p. 1445 - 1451
diisopropyl ((2-(6-amino-9H-purin-9-yl)ethoxy)methyl)phosphonate
142340-94-1

diisopropyl ((2...

~97%

Adefovir
106941-25-7

Adefovir

Literature: Green Chemistry, , vol. 14, # 8 p. 2282 - 2288
2-(6-amino-9H-purin-9-yl)ethanol
707-99-3

2-(6-amino-9H-p...

~%

Adefovir
106941-25-7

Adefovir

Literature: Collection of Czechoslovak Chemical Communications, , vol. 52, # 11 p. 2801 - 2809
Precursor & DownStream
Precursor 9 Previous 1/3 Next
Diethyl ((2-(6-amino-9H-purin-9-yl)ethoxy)methyl)phosphonate Structure CAS#:116384-53-3
Diethyl ((2-(6-...
diisopropyl ((2-(6-amino-9H-purin-9-yl)ethoxy)methyl)phosphonate Structure CAS#:142340-94-1
diisopropyl ((2...
2-(6-amino-9H-purin-9-yl)ethanol Structure CAS#:707-99-3
2-(6-amino-9H-p...
diethyl ((2-((5-amino-6-chloropyrimidin-4-yl)amino)ethoxy)methyl)phosphonate Structure CAS#:212894-84-3
diethyl ((2-((5...
DownStream 6 Previous 1/2 Next
9-[2-(dichlorophosphorylmethoxy)ethyl]purin-6-amine structure CAS#:142341-38-6
9-[2-(dichlorop...
Diethyl ((2-(6-amino-9H-purin-9-yl)ethoxy)methyl)phosphonate structure CAS#:116384-53-3
Diethyl ((2-(6-...
Adefovir Dipivoxil structure CAS#:142340-99-6
Adefovir Dipivoxil
9-[2-({bis[(pivaloyloxy)methoxy]phosphinyl}methoxy)ethyl]-6-[(hydroxymethyl)amino]purine structure CAS#:323201-04-3
9-[2-({bis[(piv...
Customs
[ HS Code ]: 2933990090
[ Summary ]: 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
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In vitro evaluation of 9-(2-phosphonylmethoxyethyl)adenine ester analogues, a series of anti-HBV structures with improved plasma stability and liver release.
Arch. Pharm. Res. 37(11) , 1416-25, (2014)

Chronic hepatitis B virus (HBV) infection may lead to liver cirrhosis and hepatocellular carcinoma, but few drugs are available for its treatment. Acyclic nucleoside phosphonates (ANPs) have remarkabl...

Detail
Quantitative high-throughput identification of drugs as modulators of human constitutive androstane receptor.
Sci. Rep. 5 , 10405, (2015)

The constitutive androstane receptor (CAR, NR1I3) plays a key role in governing the tranion of numerous hepatic genes that involve xenobiotic metabolism/clearance, energy homeostasis, and cell p...

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Surface engineered polymeric nanocarriers mediate the delivery of transferrin-methotrexate conjugates for an improved understanding of brain cancer.
Biochem. Biophys. Res. Commun. 457(3) , 353-7, (2015)

The objective of present study was to enhance permeation of bioactive molecules across blood brain barrier (BBB) through polysorbate 80 coated poly-lactic-co-glycolic acid (PLGA) nanoparticles (NPs) l...

Detail
Synonyms
gs0393
((2-(6-Amino-9H-purin-9-yl)ethoxy)methyl)phosphonic acid
MFCD00866943
PMEA

供应商信息：

公司名：济南德普顿斯化工科技有限公司

认证状态： 未认证供应商

商品数： 160件

电话： 0532-80919617

地址： 济南市高新区舜华路750号A408室

地区： 济南市市中区

联系人： 秦秀坤

联系人电话： 18153243071

邮件：bdlzhipin@aliyun.com

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Adefovir

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