Moexipril hydrochloride

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更新时间： 2022-01-12 19:51:39

CAS号：82586-52-5

常用名： 盐酸莫昔普利

价格：
$需询单/100g $需询单/1kg $需询单/100kg $需询单/1000kg

纯度： 98.0%

备货期： 需询单

库存： 询单

其他详情（用途，包装）：
用途： Moexipril HCl is a potent orally active non-sulfhydryl angiotensin converting enzyme(ACE) inhibitor, which is used for the treatment of hypertension and congestive heart failure. Target: ACEMoexipril is a long-acting ACE inhibitor suitable for once-daily administration, and like some ACE inhibitors, moexipril is a prodrug and needs to be hydrolyzed in the liver into its active carboxylic metabolite, moexiprilat, to become effective [1]. Upon oral administration of moexipril (10 mg/kg/day) to spontaneously hypertensive rats, plasma angiotensin II concentration decreased to undetectable levels, plasma ACE activity was inhibited by 98% and plasma angiotensin I concentration increased 8.6-fold 1 h after dosing. At 24 h, plasma angiotensin I and angiotensin II concentrations had returned to pretreatment levels, whereas plasma ACE activity was still inhibited by 56%. Four-week oral administration of moexipril (0.1-30 mg/kg/day) to spontaneously hypertensive rats lowered blood pressure and differentially inhibited ACE activity in plasma, lung, aorta, heart and kidney in a dose-dependent fashion [2, 3]. 物理化学性质： CAS号：82586-52-5 常用中文名：盐酸莫昔普利常用英文名：Moexipril HCl 分子式：C27H35ClN2O7 分子量：535.03 密度：N/A 沸点：709.3ºC at 760 mmHg 熔点：141-161ºC 闪点：382.8ºC 储存条件：2-8°C

供应商信息：

公司名：达阳化工（杭州）有限公司推荐

认证状态： 已认证供应商

商品数： 50193件

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联系人电话： +86-571-8893-8639

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主要市场：Mainly in Southeast Asia and European and American markets

年贸易额：10 to 20 million USD

外贸占销售比例：90%

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其他供应商价格：

2024-07-15 价格：需询单盐酸莫西普利

2021-02-06 价格：￥769.0 Moexipril HCl

2018-04-11 价格：￥需询单盐酸莫昔普利

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盐酸莫昔普利价格

Moexipril hydrochloride

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