Bisdemethoxycurcumin

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更新时间： 2022-01-28 19:58:44

CAS号：33171-05-0

常用名： 双去甲氧基姜黄素

价格：
$需询单/100g $需询单/1kg $需询单/100kg $需询单/1000kg

纯度： 98.0%

备货期： 需询单

库存： 询单

其他详情（用途，包装）：
用途： Bisdemethoxycurcumin(Curcumin III; Didemethoxycurcumin) is a natural derivative of curcumin with anti-inflammatory and anti-cancer activities.IC50 value:Target: Anticancer natural compoundin vitro: BDMC-induced apoptosis was mediated by a combinatory inhibition of cytoprotective proteins, such as Bcl2 and heme oxygenase-1 and increased generation of reactive oxygen species. Intriguingly, BDMC-induced apoptosis was reversed with co-treatment of sr144528, a cannabinoid receptor (CBR) 2 antagonist, which was confirmed with genetic downregulation of the receptor using siCBR2 [1]. Induction of cell cycle arrest in HepG2 cells by NB and BDCur in combination was evidenced by accumulation of the G2/M cell population. Further investigation on the molecular mechanism showed that NB and BDCur in combination resulted in a significant decrease in the expression level of Cdc2 and cyclin B [2]. BDMC treatment activated Sirt1/AMPK signaling pathway. Moreover, downregulating Sirt1 by the pharmacological inhibitor nicotianamine or small interfering RNA blocked BDMC-mediated protection against t-BHP-mediated decrease in proliferation [4].in vivo: human gastric adenocarcinoma xenograft model was generated in vivo using nude mice and BDMC was observed to suppress the growth and activity of tumors, in addition to improving the physical and mental capacity of the mice [3]. 物理化学性质： CAS号：33171-05-0 常用中文名：双去甲氧基姜黄素常用英文名：Bisdemethoxycurcumin 分子式：C19H16O4 分子量：308.328 密度：1.3±0.1 g/cm3 沸点：551.3±45.0 °C at 760 mmHg 熔点：221-223ºC 闪点：301.3±25.2 °C 储存条件：-20°C

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公司名：达阳化工（杭州）有限公司推荐

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2024-07-15 价格：需询单双去甲氧基姜黄素

2019-03-05 价格：￥448.0 双去甲氧基姜黄素

2021-04-03 价格：￥3150.0 Bisdemethoxycurcumin

2025-09-17 价格：￥需询单双去甲氧基姜黄素

2022-02-19 价格：￥984.9 双去甲氧基姜黄素

2017-07-06 价格：￥需询单双去甲氧基姜黄素

2017-07-05 价格：￥需询单双去甲氧基姜黄素

2018-02-11 价格：￥需询单双去甲氧基姜黄素

2018-08-14 价格：￥需询单双(二）去甲氧基姜黄素

2018-07-31 价格：￥1500.0 双去甲氧基姜黄素

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双去甲氧基姜黄素价格

Bisdemethoxycurcumin

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