Amitriptyline hydrochloride

产品详情：

发布时间： 2021-07-26 18:31:53

CAS号：549-18-8

常用名： 盐酸阿米替林

价格：
$需询单/100g $需询单/1kg $需询单/100kg $需询单/1000kg

纯度： 98.0%

备货期： 需询单

库存： 询单

其他详情（用途，包装）：
用途： Amitriptyline Hydrochloride is a dibenzocycloheptene-derivative tricyclic antidepressant (TCA).Target: OthersAmitriptyline acts primarily as a serotonin-norepinephrine reuptake inhibitor, with strong actions on the serotonin transporter and moderate effects on the norepinephrine transporter. It has negligible influence on the dopamine transporter and therefore does not affect dopamine reuptake, being nearly 1,000 times weaker on it than on serotonin [1]. Amitriptyline additionally functions as a 5-HT2A, 5-HT2C, 5-HT3, 5-HT6, 5-HT7, α1-adrenergic, H1, H2, and mACh receptorantagonist, and σ1 receptor agonist. It has also been shown to be a relatively weak NMDA receptor negative allosteric modulator at the same binding site as phencyclidine. Amitriptyline inhibits sodium channels, L-type calcium channels, and Kv1.1, Kv7.2, and Kv7.3 voltage-gated potassium channels, and therefore acts as a sodium, calcium, and potassium channel blocker as well [2]. Recently, amitriptyline has been demonstrated to act as an agonist of the TrkA and TrkB receptors. It promotes the heterodimerization of these proteins in the absence of NGF and has potent neurotrophic activity both in-vivo and in-vitro in mouse models [3]. 物理化学性质： CAS号：549-18-8 常用中文名：盐酸阿米替林常用英文名：Amitriptyline Hydrochloride 分子式：C20H24ClN 分子量：313.864 密度：1.076g/cm3 沸点：398.2ºC at 760 mmHg 熔点：196-197°C 闪点：11 °C 储存条件：2-8°C

供应商信息：

公司名：达阳化工（杭州）有限公司推荐

认证状态： 已认证供应商

商品数： 50181件

电话： +86571-88938639

地址： 浙江省杭州市西湖区文三路259号2栋9楼

地区： 杭州市西湖区

联系人： 王小姐

联系人电话： +86-571-8893-8639

邮件：enquiry@dycnchem.com

网址：http://www.dycnchem.com

主要市场：Mainly in Southeast Asia and European and American markets

年贸易额：10 to 20 million USD

外贸占销售比例：90%

主要合作伙伴：

公司介绍：

其他供应商价格：

2024-07-15 价格：需询单盐酸阿米替林

2019-03-05 价格：￥108.0 盐酸阿米替林

2022-11-29 价格：￥需询单 Amitriptyline HCl

2020-12-08 价格：￥900.0 盐酸阿米替林

2022-03-04 价格：￥37.9 盐酸阿米替林

2017-08-15 价格：￥需询单盐酸阿米替林

2018-06-14 价格：￥需询单盐酸阿米替林

2024-01-09 价格：$需询单 Amitriptyline hydrochloride

查看所有价格请点击：

盐酸阿米替林价格

Amitriptyline hydrochloride

产品详情：

供应商信息：

推荐生产厂家/供应商：

其他供应商价格：

相关产品价格：