Floxuridine

产品详情：

发布时间： 2021-07-26 18:31:53

CAS号：50-91-9

常用名： 5-氟-2'-脱氧脲核苷

价格：
$需询单/100g $需询单/1kg $需询单/100kg $需询单/1000kg

纯度： 98.0%

备货期： 需询单

库存： 询单

其他详情（用途，包装）：
用途： Floxuridine (5-fluorodeoxyuridine) is an oncology drug that belongs to the class known as antimetabolites with an GI50 of 5.1 μM for the inhibition of PEPT1. IC50 value: Target: Nucleoside antimetabolite/analogFloxuridine (Fludara) is a prodrug of floxuridine and an oncology agent with an GI50 of 5.1 μM for the inhibition of MDCK/PEPT1. Floxuridine (Fludara) belongs to the class known as antimetabolites. Floxuridine (Fludara) is most often used in the treatment of colorectal cancer. Floxuridine, an analog of 5-fluorouracil, is a fluorinated pyrimidine. Floxuridine (Fludara) works because it is broken down by the body into its active form, which is the same as a metabolite of 5-Fluorouracil [1]. FdUrd induced an immediate increase in tumor uptake of 5-[(125)I]iodo-2'-deoxyuridine, that vanished after 6 h, as also confirmed by flow cytometry. Biodistribution measurements showed that FdUrd pretreatment increased [(18)F]FLT uptake in all tumors by factors of 3.2 to 7.8 compared with controls, while [(18)F]FDG tumor uptake was about fourfold and sixfold lower in breast cancers and lymphoma. Dynamic PET in FdUrd pretreated mice showed that [(18)F]FLT uptake in all tumors increased steadily up to 1.5 h. MRI showed a well-vascularized homogenous lymphoma with high [(18)F]FLT uptake, while in breast cancer, a central necrosis shown by MRI was inactive in PET, consistent with the histomorphological analysis [2].Clinical indications: Colorectal tumor; Liver tumorFDA Approved Date: December 1970 物理化学性质： CAS号：50-91-9 常用中文名：5-氟-2'-脱氧脲核苷常用英文名：Floxuridine 分子式：C9H11FN2O5 分子量：246.192 密度：1.8±0.1 g/cm3 沸点：483.0±55.0 °C at 760 mmHg 熔点：148 °C(lit.) 闪点：245.9±31.5 °C 储存条件：2~8°C

供应商信息：

公司名：达阳化工（杭州）有限公司推荐

认证状态： 已认证供应商

商品数： 50181件

电话： +86571-88938639

地址： 浙江省杭州市西湖区文三路259号2栋9楼

地区： 杭州市西湖区

联系人： 王小姐

联系人电话： +86-571-8893-8639

邮件：enquiry@dycnchem.com

网址：http://www.dycnchem.com

主要市场：Mainly in Southeast Asia and European and American markets

年贸易额：10 to 20 million USD

外贸占销售比例：90%

主要合作伙伴：

公司介绍：

其他供应商价格：

2024-09-29 价格：￥需询单 2'-脱氧-5-氟尿苷

2022-02-19 价格：￥129.9 5-氟-2'-脱氧尿苷

2018-03-05 价格：￥需询单 5-氟-2'-脱氧脲核苷

2021-06-28 价格：￥需询单 5-F-2'-dU

2018-04-15 价格：￥需询单 5-氟-2'-脱氧脲核苷

2018-02-27 价格：$需询单 5-Fluoro-2'-Deoxyuridine

2023-02-20 价格：￥需询单 5-氟-2'-脱氧尿苷

2021-02-06 价格：￥359.0 Floxuridine

2024-01-09 价格：$需询单 5-fluoro-2'-deoxyuridine

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5-氟-2'-脱氧脲核苷价格

Floxuridine

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