Valaciclovir
产品详情:
更新时间: 2023-02-23 20:13:43
CAS号:124832-26-4
常用名:
价格:
$需询单/100g
$需询单/1kg
$需询单/100kg
$需询单/1000kg
纯度: 98.0%
备货期: 需询单
库存: 询单
其他详情(用途,包装):
用途: Valacyclovir is an antiviral drug used in the management of herpes simplex, herpes zoster, and herpes B. IC50 Value: 2.9 microg/ml (for HSV-1 W)[4]. Target: HSV infectionin vitro: VACV uptake was concentration dependent and saturable with a Michaelis-Menten constant and maximum velocity of 1.64 +/- 0.06 mM and 23.34 +/- 0.36 nmol/mg protein/5 min, respectively. A very similar Km value was obtained in hPEPT1/CHO cells and in rat and rabbit tissues and Caco-2 cells, suggesting that hPEPT1 dominates the intestinal transport properties of VACV in vitro [5]. in vivo: For treatment of a first episode of genital herpes, a large comparative trial has shown that valacyclovir (1 g twice a day) is as effective as acyclovir (200 mg five times a day) when given for 10 days. For treating recurrences, two trials show that valacyclovir is as effective as acyclovir (200 mg five times a day) with a treatment period of 5 days. A daily dose of 1 g of valacyclovir is as effective as 2 g daily. Valacyclovir can be administered once a day[1]. The concentrations of acyclovir in serum and CSF were measured at steady state after 6 days of oral treatment with 1,000 mg of valacyclovir three times a day [2]. EC50 values of PE and AC in 3T3 cells were 0.02 and 0.01 ug/ml, while values in BHK cells were 0.2 and 0.03 ug/ml. Treatment of infected immunosuppressed mice and FA and VA (b.i.d., 5.5 days) reduced the proportion with erythema from 100% to 24% and 38%, and eliminated ear paralysis, ear lesions (vesicles, etc) and death. Virus was absent from ear and brainstem by day 6, but reappeared after discontinuation in mice treated with VA [3].Clinical trial: Evaluation of Valaciclovir in Patients with Chickenpox. Phage3 物理化学性质: CAS号:124832-26-4 常用中文名:伐昔洛韦 常用英文名:Valacyclovir 分子式:C13H20N6O4 分子量:324.336 密度:1.5±0.1 g/cm3 沸点:N/A 熔点:N/A 闪点:309.7ºC 储存条件:2-8℃
供应商信息:
公司名:达阳化工(杭州)有限公司 推荐
认证状态: 已认证供应商
商品数: 48443件
电话: +86571-88938639
地址: 浙江省杭州市西湖区文三路259号2栋9楼
地区: 杭州市西湖区
联系人: 王小姐
联系人电话: +86-571-8893-8639
邮件:enquiry@dycnchem.com
主要市场:Mainly in Southeast Asia and European and American markets
年贸易额:10 to 20 million USD
外贸占销售比例:90%
主要合作伙伴:
公司介绍:
推荐生产厂家/供应商:
公司名:苏州市森菲达化工有限公司
区域:苏州市相城区
价格:
¥需询单/200kg
联系人:程经理
产品详情:
公司名:上海化源世纪贸易有限公司
区域:上海市普陀区
价格:
联系人:徐经理
产品详情:
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其他供应商价格:
2026-03-10 价格:¥需询单
2024-07-15 价格:需询单
2021-02-06 价格:¥827.0
2024-01-09 价格:$需询单
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相关产品价格:
Valaciclovir价格为$需询单/100g, 由Valaciclovir生产厂家达阳化工(杭州)有限公司提供,供应信息包括纯度,备货期/库存,供货能力等。>>电脑版:Valaciclovir_价格_生产厂家【达阳化工(杭州)有限公司】
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