Imidafenacin

产品详情：

发布时间： 2021-07-26 18:31:53

CAS号：170105-16-5

常用名： 咪达那新

价格：
$需询单/100g $需询单/1kg $需询单/100kg $需询单/1000kg

纯度： 98.0%

备货期： 需询单

库存： 询单

其他详情（用途，包装）：
用途： Imidafenacin(KRP-197; ONO-8025) is a potent and selective inhibitor of M3 receptors with Kb of 0.317 nM; less potent for M2 receptors(IC50=4.13 nM).IC50 value: 0.3 nM(M3) [1]in vitro: KRP-197 showed equipotent anti-M2 and anti-M3 activity and decreased subtype-selectivity [1]. in vivo: Intraduodenal administration of KRP-197 (0.04±0.30 mg/kg) inhibited bladder contraction dose-dependently, and the ED30 value was 0.11 mg/kg. The inhibitory action of KRP-197 on the bladder contraction was 19 times as potent as that of oxybutynin. KRP-197 showed preventive action againstthe decrease in bladder capacity induced by carbachol(ED50 0.074 mg/kg, intragastric administration), andthe potency of the inhibitory action was 15-fold greaterthan that of oxybutynin [1]. The learning-inhibitory doses of intravenous oxybutynin hydrochloride and tolterodine tartrate were 0.3 and 3 mg/kg in sham-operated rats and 0.1 and 1 mg/kg in nbM-lesioned rats, respectively. Thus, the learning impairments by those antimuscarinics were more sensitive in nbM-lesioned rats than in sham-operated rats. On the other hand, intravenous administration of imidafenacin had no influence on learning in either case of the rats. In normal rats, however, intracerebroventricular administration of imidafenacin impaired learning to the same degree as that of oxybutynin hydrochloride [2]. 物理化学性质： CAS号：170105-16-5 常用中文名：咪达那新常用英文名：Imidafenacin 分子式：C20H21N3O 分子量：319.400 密度：1.1±0.1 g/cm3 沸点：579.7±50.0 °C at 760 mmHg 熔点：N/A 闪点：304.4±30.1 °C 储存条件：2-8℃

供应商信息：

公司名：达阳化工（杭州）有限公司推荐

认证状态： 已认证供应商

商品数： 50181件

电话： +86571-88938639

地址： 浙江省杭州市西湖区文三路259号2栋9楼

地区： 杭州市西湖区

联系人： 王小姐

联系人电话： +86-571-8893-8639

邮件：enquiry@dycnchem.com

网址：http://www.dycnchem.com

主要市场：Mainly in Southeast Asia and European and American markets

年贸易额：10 to 20 million USD

外贸占销售比例：90%

主要合作伙伴：

公司介绍：

其他供应商价格：

2024-03-12 价格：￥399.9 咪唑啉

2025-09-17 价格：￥需询单咪达那新

2017-06-12 价格：￥需询单咪达那新

2017-07-03 价格：￥需询单咪达那新

2017-12-08 价格：￥需询单咪达那新

2017-06-18 价格：￥需询单咪达那新杂质

2022-08-23 价格：￥需询单咪达非那辛

2019-06-14 价格：￥需询单咪达那新

2024-01-09 价格：$需询单 C20H21N3O Imidafenacin 170105-16-5

查看所有价格请点击：

咪达那新价格

Imidafenacin

产品详情：

供应商信息：

推荐生产厂家/供应商：

其他供应商价格：

相关产品价格：