Dorzolomide hydrochloride

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更新时间： 2022-02-25 19:49:35

CAS号：130693-82-2

常用名： 盐酸多佐胺

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$需询单/100g $需询单/1kg $需询单/100kg $需询单/1000kg

纯度： 98.0%

备货期： 需询单

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其他详情（用途，包装）：
用途： Dorzolamide Hcl(L671152 Hcl; MK507 Hcl) is an anti-glaucoma agent, which is a carbonic anhydrase inhibitor.Target: carbonic anhydrase (CA)Dorzolamide hydrochloride is a carbonic anhydrase inhibitor. It is an anti-glaucoma agent, and acts by decreasing the production of aqueous humour [1]. Glaucoma was induced in the right eye of adult Wistar rats by episcleral venous occlusion. One experimental group was administered dorzolamide hydrochloride 2%-timolol 0.5% combination eye drops, while the other experimental group was administered dorzolamide hydrochloride2% eye drops. Control groups had surgery without drug administration. Drug application was initiated either 2 weeks before surgery (Group A), from the day of surgery (Group B), 2 weeks after surgery (Group C), or 4 weeks after surgery (Group D). RGCs were labeled by intratectal Fluorogold injections and counted from flat-mount preparations, and IOP was measured using Tonopen. Both dorzolamide-timolol combination and dorzolamide hydrochloride, when applied topically, significantly reduced IOP and improved RGC densities in experimental eyes when compared to control eyes. Earlier initiation, as well as longer duration of drug application, resulted in higher RGC densities [2].Clinical indications: Glaucoma; Ocular hypertensionFDA Approved Date: 1995Toxicity: Dizziness, headache, shortness of breath, slow heartbeat, severe asthma, cardiac arrest 物理化学性质： CAS号：130693-82-2 常用中文名：盐酸多佐胺常用英文名：Dorzolamide hydrochloride 分子式：C10H17ClN2O4S3 分子量：360.90100 密度：1.53 g/cm3 沸点：575.8ºC at 760 mmHg 熔点：283-285ºC 闪点：302ºC 储存条件：Refrigerator

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公司名：达阳化工（杭州）有限公司推荐

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盐酸多佐胺价格

Dorzolomide hydrochloride

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