sodium 5-(aminosulphonyl)-4-chloro-2-(furan-2-ylmethyl)anthranilate

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更新时间： 2024-04-09 19:26:15

CAS号：41733-55-5

常用名： 呋塞米钠

价格：
$需询单/100g $需询单/1kg $需询单/100kg $需询单/1000kg

纯度： 98.0%

备货期： 需询单

库存： 询单

其他详情（用途，包装）：
用途： Furosemide sodium (Lasix) is a loop diuretic inhibitor of Na+/2Cl-/K+ (NKCC) cotransporter of which used in the treatment of congestive heart failure and edema.Target: NKCC Furosemide (INN/BAN) or frusemide is a loop diuretic used in the treatment of congestive heart failure and edema. It is most commonly marketed by Sanofi under the brand name Lasix, and also under the brand names Fusid and Frumex. It has also been used to prevent Thoroughbred and Standardbred race horses from bleeding through the nose during races.Along with some other diuretics, furosemide is also included on the World Anti-Doping Agency's banned drug list due to its alleged use as a masking agent for other drugs.Furosemide, like other loop diuretics, acts by inhibiting NKCC2, the luminal Na-K-2Cl symporter in the thick ascending limb of the loop of Henle. The action on the distal tubules is independent of any inhibitory effect on carbonic anhydrase or aldosterone; it also abolishes the corticomedullary osmotic gradient and blocks negative, as well as positive, free water clearance.Because of the large NaCl absorptive capacity of the loop of Henle, diuresis is not limited by development of acidosis, as it is with the carbonic anhydrase inhibitors. Additionally, furosemide is a noncompetitive subtype-specific blocker of GABA-A receptors. Furosemide has been reported to reversibly antagonize GABA-evoked currents of α6β2γ2 receptors at ?M concentrations, but not α1β2γ2 receptors. During development, the α6β2γ2 receptor increases in expression in cerebellar granule neurons, corresponding to increased sensitivity to furosemide 物理化学性质： CAS号：41733-55-5 常用中文名：呋塞米钠常用英文名：Furosemide (sodium) 分子式：C12H10ClN2NaO5S 分子量：352.72600 密度：N/A 沸点：582.1ºC at 760 mmHg 熔点：206ºC 闪点：305.9ºC 储存条件：2-8℃

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其他供应商价格：

2024-07-15 价格：需询单 Furosemide sodium?

2022-09-23 价格：￥1000.0 呋塞米钠

2024-03-12 价格：￥269.9 呋塞米钠

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呋塞米钠价格

sodium 5-(aminosulphonyl)-4-chloro-2-(furan-2-ylmethyl)anthranilate

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