Benzamide, 4-(4-ethyl-5-fluoro-2-hydroxyphenoxy)-3-fluoro-
产品详情：
更新时间： 2023-10-09 17:28:13
CAS号：1269055-85-7
常用名：
价格：
$需询单/100g
$需询单/1kg
$需询单/100kg
$需询单/1000kg
纯度： 98.0%
备货期： 需询单
库存： 询单
其他详情（用途，包装）：
用途： MUT056399 is a highly potent inhibitor of the FabI enzyme of both S. aureus and E. coli with 50% inhibitory concentration IC50s of 12 nM and 58 nM, respectively. IC50 value: 12 nM (for S. aureus), 58 nM (for E. coli) [1]Target: FabI enzymein vitro: MUT056399 is a highly potent new inhibitor of the FabI enzyme of both Staphylococcus aureus and Escherichia coli. MUT056399 is very active against S. aureus strains, including methicillin-susceptible S. aureus (MSSA), methicillin-resistant S. aureus (MRSA), linezolid-resistant, and multidrug-resistant strains, with MIC90s between 0.03 and 0.12 μg/ml. MUT056399 is also active against coagulase-negative staphylococci, with MIC90s between 0.12 and 4 μg/ml. MUT056399 is very active against the 118 S. aureus strains tested, including MSSA and MRSA isolates and linezolid-resistant and multidrug-resistant strains, with MIC90s between ≤0.03 and 0.12 μg/ml.In vivo: MUT056399, administered subcutaneously, protected mice from a lethal systemic infection induced by MSSA, MRSA, and vancomycin-intermediate S. aureus strains (50% effective doses ranging from 19.3 mg/kg/day to 49.6 mg/kg/day). In the nonneutropenic murine thigh infection model, the same treatment with MUT056399 reduced the bacterial multiplication of MSSA and MRSA in the thighs of immunocompetent mice. 物理化学性质： CAS号：1269055-85-7 常用中文名：MUT056399 常用英文名：MUT056399 分子式：C15H13F2NO3 分子量：293.265 密度：1.3±0.1 g/cm3 沸点：373.8±42.0 °C at 760 mmHg 熔点：N/A 闪点：179.9±27.9 °C 储存条件：2-8℃
供应商信息：
公司名：达阳化工（杭州）有限公司 推荐
认证状态： 已认证供应商
商品数： 48264件
电话： +86571-88938639
地址： 浙江省杭州市西湖区文三路259号2栋9楼
地区： 杭州市西湖区
联系人： 王小姐
联系人电话： +86-571-8893-8639
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主要市场：Mainly in Southeast Asia and European and American markets
年贸易额：10 to 20 million USD
外贸占销售比例：90%
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2024-07-15 价格：需询单
2022-09-23 价格：￥2667.0
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Benzamide, 4-(4-ethyl-5-fluoro-2-hydroxyphenoxy)-3-fluoro-价格为$需询单/100g, 由Benzamide, 4-(4-ethyl-5-fluoro-2-hydroxyphenoxy)-3-fluoro-生产厂家达阳化工（杭州）有限公司提供，供应信息包括纯度，备货期/库存，供货能力等。>>电脑版：Benzamide, 4-(4-ethyl-5-fluoro-2-hydroxyphenoxy)-3-fluoro-_价格_生产厂家【达阳化工（杭州）有限公司】
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